Minimum Information about a Biosynthetic Gene cluster: commentary

Marnix H Medema; Renzo Kottmann; Pelin Yilmaz; Matthew Cummings; John B Biggins; Kai Blin; Irene de Bruijn; Yit Heng Chooi; Jan Claesen; R Cameron Coates; Pablo Cruz-Morales; Srikanth Duddela; Stephanie Dusterhus; Daniel J Edwards; David P Fewer; Neha Garg; Christoph Geiger; Juan Pablo Gomez-Escribano; Anja Greule; Michalis Hadjithomas; Anthony S Haines; Eric J N Helfrich; Matthew L Hillwig; Keishi Ishida; Adam C Jones; Carla S Jones; Katrin Jungmann; Carsten Kegler; Hyun Uk Kim; Peter Kotter; Daniel Krug; Joleen Masschelein; Alexey V Melnik; Simone M Mantovani; Emily A Monroe; Marcus Moore; Nathan Moss; Hans-Wilhelm Nutzmann; Guohui Pan; Amrita Pati; Daniel Petras; F Jerry Reen; Federico Rosconi; Zhe Rui; Zhenhua Tian; Nicholas J Tobias; Yuta Tsunematsu; Philipp Wiemann; Elizabeth Wyckoff; Xiaohui Yan; Grace Yim; Fengan Yu; Yunchang Xie; Bertrand Aigle; Alexander K Apel; Carl J Balibar; Emily P Balskus; Francisco Barona-Gomez; Andreas Bechthold; Helge B Bode; Rainer Borriss; Sean F Brady; Axel A Brakhage; Patrick Caffrey; Yi-Qiang Cheng; Jon Clardy; Russell J Cox; Rene De Mot; Stefano Donadio; Mohamed S Donia; Wilfred A van der Donk; Pieter C Dorrestein; Sean Doyle; Arnold J M Driessen; Monika Ehling-Schulz; Karl-Dieter Entian; Michael A Fischbach; Lena Gerwick; William H Gerwick; Harald Gross; Bertolt Gust; Christian Hertweck; Monica Hofte; Susan E Jensen; Jianhua Ju; Leonard Katz; Leonard Kaysser; Jonathan L Klassen; Nancy P Keller; Jan Kormanec; Oscar P Kuipers; Tomohisa Kuzuyama; Nikos C Kyrpides; Hyung-Jin Kwon; Sylvie Lautru; Rob Lavigne; Chia Y Lee; Bai Linquan; Xinyu Liu; Wen Liu; Andriy Luzhetskyy; Taifo Mahmud; Yvonne Mast; Carmen Mendez; Mikko Metsa-Ketela; Jason Micklefield; Douglas A Mitchell; Bradley S Moore; Leonilde M Moreira; Rolf Muller; Brett A Neilan; Markus Nett; Jens Nielsen; Fergal O'Gara; Hideaki Oikawa; Anne Osbourn; Marcia S Osburne; Bohdan Ostash; Shelley M Payne; Jean-Luc Pernodet; Miroslav Petricek; Jorn Piel; Olivier Ploux; Jos M Raaijmakers; Jose A Salas; Esther K Schmitt; Barry Scott; Ryan F Seipke; Ben Shen; David H Sherman; Kaarina Sivonen; Michael J Smanski; Margherita Sosio; Evi Stegmann; Roderich D Sussmuth; Kapil Tahlan; Christopher M Thomas; Yi Tang; Andrew W Truman; Muriel Viaud; Jonathan D Walton; Christopher T Walsh; Tilmann Weber; Gilles P van Wezel; Barrie Wilkinson; Joanne M Willey; Wolfgang Wohlleben; Gerard D Wright; Nadine Ziemert; Changsheng Zhang; Sergey B Zotchev; Rainer Breitling; Eriko Takano; Frank Oliver Glockner

doi:10.1038/nchembio.1890

Minimum Information about a Biosynthetic Gene cluster: commentary

Marnix H Medema, Renzo Kottmann, Pelin Yilmaz, Matthew Cummings, John B Biggins, Kai Blin, Irene de Bruijn, Yit Heng Chooi, Jan Claesen, R Cameron Coates, Pablo Cruz-Morales, Srikanth Duddela, Stephanie Dusterhus, Daniel J Edwards, David P Fewer, Neha Garg, Christoph Geiger, Juan Pablo Gomez-Escribano, Anja Greule, Michalis HadjithomasAnthony S Haines, Eric J N Helfrich, Matthew L Hillwig, Keishi Ishida, Adam C Jones, Carla S Jones, Katrin Jungmann, Carsten Kegler, Hyun Uk Kim, Peter Kotter, Daniel Krug, Joleen Masschelein, Alexey V Melnik, Simone M Mantovani, Emily A Monroe, Marcus Moore, Nathan Moss, Hans-Wilhelm Nutzmann, Guohui Pan, Amrita Pati, Daniel Petras, F Jerry Reen, Federico Rosconi, Zhe Rui, Zhenhua Tian, Nicholas J Tobias, Yuta Tsunematsu, Philipp Wiemann, Elizabeth Wyckoff, Xiaohui Yan, Grace Yim, Fengan Yu, Yunchang Xie, Bertrand Aigle, Alexander K Apel, Carl J Balibar, Emily P Balskus, Francisco Barona-Gomez, Andreas Bechthold, Helge B Bode, Rainer Borriss, Sean F Brady, Axel A Brakhage, Patrick Caffrey, Yi-Qiang Cheng, Jon Clardy, Russell J Cox, Rene De Mot, Stefano Donadio, Mohamed S Donia, Wilfred A van der Donk, Pieter C Dorrestein, Sean Doyle, Arnold J M Driessen, Monika Ehling-Schulz, Karl-Dieter Entian, Michael A Fischbach, Lena Gerwick, William H Gerwick, Harald Gross, Bertolt Gust, Christian Hertweck, Monica Hofte, Susan E Jensen, Jianhua Ju, Leonard Katz, Leonard Kaysser, Jonathan L Klassen, Nancy P Keller, Jan Kormanec, Oscar P Kuipers, Tomohisa Kuzuyama, Nikos C Kyrpides, Hyung-Jin Kwon, Sylvie Lautru, Rob Lavigne, Chia Y Lee, Bai Linquan, Xinyu Liu, Wen Liu, Andriy Luzhetskyy, Taifo Mahmud, Yvonne Mast, Carmen Mendez, Mikko Metsa-Ketela, Jason Micklefield, Douglas A Mitchell, Bradley S Moore, Leonilde M Moreira, Rolf Muller, Brett A Neilan, Markus Nett, Jens Nielsen, Fergal O'Gara, Hideaki Oikawa, Anne Osbourn, Marcia S Osburne, Bohdan Ostash, Shelley M Payne, Jean-Luc Pernodet, Miroslav Petricek, Jorn Piel, Olivier Ploux, Jos M Raaijmakers, Jose A Salas, Esther K Schmitt, Barry Scott, Ryan F Seipke, Ben Shen, David H Sherman, Kaarina Sivonen, Michael J Smanski, Margherita Sosio, Evi Stegmann, Roderich D Sussmuth, Kapil Tahlan, Christopher M Thomas, Yi Tang, Andrew W Truman, Muriel Viaud, Jonathan D Walton, Christopher T Walsh, Tilmann Weber, Gilles P van Wezel, Barrie Wilkinson, Joanne M Willey, Wolfgang Wohlleben, Gerard D Wright, Nadine Ziemert, Changsheng Zhang, Sergey B Zotchev, Rainer Breitling, Eriko Takano, Frank Oliver Glockner

NIOO - Microbial Ecology (ME)

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

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Abstract

A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants
are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and
metabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitate
consistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose the
Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.

Original language	English
Pages (from-to)	625-631
Number of pages	7
Journal	Nature Chemical Biology
Volume	11
Issue number	9
DOIs	https://doi.org/10.1038/nchembio.1890
Publication status	Published - Sept 2015

Keywords

international

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10.1038/nchembio.1890

5939_Medema
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Medema, M. H., Kottmann, R., Yilmaz, P., Cummings, M., Biggins, J. B., Blin, K., de Bruijn, I., Chooi, Y. H., Claesen, J., Coates, R. C., Cruz-Morales, P., Duddela, S., Dusterhus, S., Edwards, D. J., Fewer, D. P., Garg, N., Geiger, C., Gomez-Escribano, J. P., Greule, A., ... Glockner, F. O. (2015). Minimum Information about a Biosynthetic Gene cluster: commentary. Nature Chemical Biology, 11(9), 625-631. https://doi.org/10.1038/nchembio.1890

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abstract = "A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plantsare known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways andmetabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitateconsistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose theMinimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.",

keywords = "international",

author = "Medema, {Marnix H} and Renzo Kottmann and Pelin Yilmaz and Matthew Cummings and Biggins, {John B} and Kai Blin and {de Bruijn}, Irene and Chooi, {Yit Heng} and Jan Claesen and Coates, {R Cameron} and Pablo Cruz-Morales and Srikanth Duddela and Stephanie Dusterhus and Edwards, {Daniel J} and Fewer, {David P} and Neha Garg and Christoph Geiger and Gomez-Escribano, {Juan Pablo} and Anja Greule and Michalis Hadjithomas and Haines, {Anthony S} and Helfrich, {Eric J N} and Hillwig, {Matthew L} and Keishi Ishida and Jones, {Adam C} and Jones, {Carla S} and Katrin Jungmann and Carsten Kegler and Kim, {Hyun Uk} and Peter Kotter and Daniel Krug and Joleen Masschelein and Melnik, {Alexey V} and Mantovani, {Simone M} and Monroe, {Emily A} and Marcus Moore and Nathan Moss and Hans-Wilhelm Nutzmann and Guohui Pan and Amrita Pati and Daniel Petras and Reen, {F Jerry} and Federico Rosconi and Zhe Rui and Zhenhua Tian and Tobias, {Nicholas J} and Yuta Tsunematsu and Philipp Wiemann and Elizabeth Wyckoff and Xiaohui Yan and Grace Yim and Fengan Yu and Yunchang Xie and Bertrand Aigle and Apel, {Alexander K} and Balibar, {Carl J} and Balskus, {Emily P} and Francisco Barona-Gomez and Andreas Bechthold and Bode, {Helge B} and Rainer Borriss and Brady, {Sean F} and Brakhage, {Axel A} and Patrick Caffrey and Yi-Qiang Cheng and Jon Clardy and Cox, {Russell J} and {De Mot}, Rene and Stefano Donadio and Donia, {Mohamed S} and {van der Donk}, {Wilfred A} and Dorrestein, {Pieter C} and Sean Doyle and Driessen, {Arnold J M} and Monika Ehling-Schulz and Karl-Dieter Entian and Fischbach, {Michael A} and Lena Gerwick and Gerwick, {William H} and Harald Gross and Bertolt Gust and Christian Hertweck and Monica Hofte and Jensen, {Susan E} and Jianhua Ju and Leonard Katz and Leonard Kaysser and Klassen, {Jonathan L} and Keller, {Nancy P} and Jan Kormanec and Kuipers, {Oscar P} and Tomohisa Kuzuyama and Kyrpides, {Nikos C} and Hyung-Jin Kwon and Sylvie Lautru and Rob Lavigne and Lee, {Chia Y} and Bai Linquan and Xinyu Liu and Wen Liu and Andriy Luzhetskyy and Taifo Mahmud and Yvonne Mast and Carmen Mendez and Mikko Metsa-Ketela and Jason Micklefield and Mitchell, {Douglas A} and Moore, {Bradley S} and Moreira, {Leonilde M} and Rolf Muller and Neilan, {Brett A} and Markus Nett and Jens Nielsen and Fergal O'Gara and Hideaki Oikawa and Anne Osbourn and Osburne, {Marcia S} and Bohdan Ostash and Payne, {Shelley M} and Jean-Luc Pernodet and Miroslav Petricek and Jorn Piel and Olivier Ploux and Raaijmakers, {Jos M} and Salas, {Jose A} and Schmitt, {Esther K} and Barry Scott and Seipke, {Ryan F} and Ben Shen and Sherman, {David H} and Kaarina Sivonen and Smanski, {Michael J} and Margherita Sosio and Evi Stegmann and Sussmuth, {Roderich D} and Kapil Tahlan and Thomas, {Christopher M} and Yi Tang and Truman, {Andrew W} and Muriel Viaud and Walton, {Jonathan D} and Walsh, {Christopher T} and Tilmann Weber and {van Wezel}, {Gilles P} and Barrie Wilkinson and Willey, {Joanne M} and Wolfgang Wohlleben and Wright, {Gerard D} and Nadine Ziemert and Changsheng Zhang and Zotchev, {Sergey B} and Rainer Breitling and Eriko Takano and Glockner, {Frank Oliver}",

note = "5939, ME; Data archiving: Property of and archived at WUR ",

year = "2015",

month = sep,

doi = "10.1038/nchembio.1890",

language = "English",

volume = "11",

pages = "625--631",

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Medema, MH, Kottmann, R, Yilmaz, P, Cummings, M, Biggins, JB, Blin, K, de Bruijn, I, Chooi, YH, Claesen, J, Coates, RC, Cruz-Morales, P, Duddela, S, Dusterhus, S, Edwards, DJ, Fewer, DP, Garg, N, Geiger, C, Gomez-Escribano, JP, Greule, A, Hadjithomas, M, Haines, AS, Helfrich, EJN, Hillwig, ML, Ishida, K, Jones, AC, Jones, CS, Jungmann, K, Kegler, C, Kim, HU, Kotter, P, Krug, D, Masschelein, J, Melnik, AV, Mantovani, SM, Monroe, EA, Moore, M, Moss, N, Nutzmann, H-W, Pan, G, Pati, A, Petras, D, Reen, FJ, Rosconi, F, Rui, Z, Tian, Z, Tobias, NJ, Tsunematsu, Y, Wiemann, P, Wyckoff, E, Yan, X, Yim, G, Yu, F, Xie, Y, Aigle, B, Apel, AK, Balibar, CJ, Balskus, EP, Barona-Gomez, F, Bechthold, A, Bode, HB, Borriss, R, Brady, SF, Brakhage, AA, Caffrey, P, Cheng, Y-Q, Clardy, J, Cox, RJ, De Mot, R, Donadio, S, Donia, MS, van der Donk, WA, Dorrestein, PC, Doyle, S, Driessen, AJM, Ehling-Schulz, M, Entian, K-D, Fischbach, MA, Gerwick, L, Gerwick, WH, Gross, H, Gust, B, Hertweck, C, Hofte, M, Jensen, SE, Ju, J, Katz, L, Kaysser, L, Klassen, JL, Keller, NP, Kormanec, J, Kuipers, OP, Kuzuyama, T, Kyrpides, NC, Kwon, H-J, Lautru, S, Lavigne, R, Lee, CY, Linquan, B, Liu, X, Liu, W, Luzhetskyy, A, Mahmud, T, Mast, Y, Mendez, C, Metsa-Ketela, M, Micklefield, J, Mitchell, DA, Moore, BS, Moreira, LM, Muller, R, Neilan, BA, Nett, M, Nielsen, J, O'Gara, F, Oikawa, H, Osbourn, A, Osburne, MS, Ostash, B, Payne, SM, Pernodet, J-L, Petricek, M, Piel, J, Ploux, O, Raaijmakers, JM, Salas, JA, Schmitt, EK, Scott, B, Seipke, RF, Shen, B, Sherman, DH, Sivonen, K, Smanski, MJ, Sosio, M, Stegmann, E, Sussmuth, RD, Tahlan, K, Thomas, CM, Tang, Y, Truman, AW, Viaud, M, Walton, JD, Walsh, CT, Weber, T, van Wezel, GP, Wilkinson, B, Willey, JM, Wohlleben, W, Wright, GD, Ziemert, N, Zhang, C, Zotchev, SB, Breitling, R, Takano, E & Glockner, FO 2015, 'Minimum Information about a Biosynthetic Gene cluster: commentary', Nature Chemical Biology, vol. 11, no. 9, pp. 625-631. https://doi.org/10.1038/nchembio.1890

TY - JOUR

T1 - Minimum Information about a Biosynthetic Gene cluster

T2 - commentary

AU - Medema, Marnix H

AU - Kottmann, Renzo

AU - Yilmaz, Pelin

AU - Cummings, Matthew

AU - Biggins, John B

AU - Blin, Kai

AU - de Bruijn, Irene

AU - Chooi, Yit Heng

AU - Claesen, Jan

AU - Coates, R Cameron

AU - Cruz-Morales, Pablo

AU - Duddela, Srikanth

AU - Dusterhus, Stephanie

AU - Edwards, Daniel J

AU - Fewer, David P

AU - Garg, Neha

AU - Geiger, Christoph

AU - Gomez-Escribano, Juan Pablo

AU - Greule, Anja

AU - Hadjithomas, Michalis

AU - Haines, Anthony S

AU - Helfrich, Eric J N

AU - Hillwig, Matthew L

AU - Ishida, Keishi

AU - Jones, Adam C

AU - Jones, Carla S

AU - Jungmann, Katrin

AU - Kegler, Carsten

AU - Kim, Hyun Uk

AU - Kotter, Peter

AU - Krug, Daniel

AU - Masschelein, Joleen

AU - Melnik, Alexey V

AU - Mantovani, Simone M

AU - Monroe, Emily A

AU - Moore, Marcus

AU - Moss, Nathan

AU - Nutzmann, Hans-Wilhelm

AU - Pan, Guohui

AU - Pati, Amrita

AU - Petras, Daniel

AU - Reen, F Jerry

AU - Rosconi, Federico

AU - Rui, Zhe

AU - Tian, Zhenhua

AU - Tobias, Nicholas J

AU - Tsunematsu, Yuta

AU - Wiemann, Philipp

AU - Wyckoff, Elizabeth

AU - Yan, Xiaohui

AU - Yim, Grace

AU - Yu, Fengan

AU - Xie, Yunchang

AU - Aigle, Bertrand

AU - Apel, Alexander K

AU - Balibar, Carl J

AU - Balskus, Emily P

AU - Barona-Gomez, Francisco

AU - Bechthold, Andreas

AU - Bode, Helge B

AU - Borriss, Rainer

AU - Brady, Sean F

AU - Brakhage, Axel A

AU - Caffrey, Patrick

AU - Cheng, Yi-Qiang

AU - Clardy, Jon

AU - Cox, Russell J

AU - De Mot, Rene

AU - Donadio, Stefano

AU - Donia, Mohamed S

AU - van der Donk, Wilfred A

AU - Dorrestein, Pieter C

AU - Doyle, Sean

AU - Driessen, Arnold J M

AU - Ehling-Schulz, Monika

AU - Entian, Karl-Dieter

AU - Fischbach, Michael A

AU - Gerwick, Lena

AU - Gerwick, William H

AU - Gross, Harald

AU - Gust, Bertolt

AU - Hertweck, Christian

AU - Hofte, Monica

AU - Jensen, Susan E

AU - Ju, Jianhua

AU - Katz, Leonard

AU - Kaysser, Leonard

AU - Klassen, Jonathan L

AU - Keller, Nancy P

AU - Kormanec, Jan

AU - Kuipers, Oscar P

AU - Kuzuyama, Tomohisa

AU - Kyrpides, Nikos C

AU - Kwon, Hyung-Jin

AU - Lautru, Sylvie

AU - Lavigne, Rob

AU - Lee, Chia Y

AU - Linquan, Bai

AU - Liu, Xinyu

AU - Liu, Wen

AU - Luzhetskyy, Andriy

AU - Mahmud, Taifo

AU - Mast, Yvonne

AU - Mendez, Carmen

AU - Metsa-Ketela, Mikko

AU - Micklefield, Jason

AU - Mitchell, Douglas A

AU - Moore, Bradley S

AU - Moreira, Leonilde M

AU - Muller, Rolf

AU - Neilan, Brett A

AU - Nett, Markus

AU - Nielsen, Jens

AU - O'Gara, Fergal

AU - Oikawa, Hideaki

AU - Osbourn, Anne

AU - Osburne, Marcia S

AU - Ostash, Bohdan

AU - Payne, Shelley M

AU - Pernodet, Jean-Luc

AU - Petricek, Miroslav

AU - Piel, Jorn

AU - Ploux, Olivier

AU - Raaijmakers, Jos M

AU - Salas, Jose A

AU - Schmitt, Esther K

AU - Scott, Barry

AU - Seipke, Ryan F

AU - Shen, Ben

AU - Sherman, David H

AU - Sivonen, Kaarina

AU - Smanski, Michael J

AU - Sosio, Margherita

AU - Stegmann, Evi

AU - Sussmuth, Roderich D

AU - Tahlan, Kapil

AU - Thomas, Christopher M

AU - Tang, Yi

AU - Truman, Andrew W

AU - Viaud, Muriel

AU - Walton, Jonathan D

AU - Walsh, Christopher T

AU - Weber, Tilmann

AU - van Wezel, Gilles P

AU - Wilkinson, Barrie

AU - Willey, Joanne M

AU - Wohlleben, Wolfgang

AU - Wright, Gerard D

AU - Ziemert, Nadine

AU - Zhang, Changsheng

AU - Zotchev, Sergey B

AU - Breitling, Rainer

AU - Takano, Eriko

AU - Glockner, Frank Oliver

N1 - 5939, ME; Data archiving: Property of and archived at WUR

PY - 2015/9

Y1 - 2015/9

N2 - A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plantsare known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways andmetabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitateconsistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose theMinimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.

AB - A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plantsare known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways andmetabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitateconsistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose theMinimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.

KW - international

U2 - 10.1038/nchembio.1890

DO - 10.1038/nchembio.1890

M3 - Article

SN - 1552-4450

VL - 11

SP - 625

EP - 631

JO - Nature Chemical Biology

JF - Nature Chemical Biology

IS - 9

ER -

Minimum Information about a Biosynthetic Gene cluster: commentary

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