Neuronal Cytoskeleton: Presynaptic Boutons as Hotspots for Activity-Dependent Microtubule Nucleation

Amélie Freal; Casper C Hoogenraad

doi:10.1016/j.cub.2019.11.011

Neuronal Cytoskeleton: Presynaptic Boutons as Hotspots for Activity-Dependent Microtubule Nucleation

Amélie Freal, Casper C Hoogenraad

Netherlands Institute for Neuroscience (NIN)

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

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Abstract

Local microtubule remodeling plays a crucial role in controlling the transport of neuronal cargo. A new study reveals that excitatory en passant boutons in the axon are hotspots for activity-induced microtubule nucleation and provide tracks for interbouton vesicle trafficking.

Original language	English
Pages (from-to)	R1307-R1309
Journal	Current Biology
Volume	29
Issue number	24
DOIs	https://doi.org/10.1016/j.cub.2019.11.011
Publication status	Published - 2019

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Freal et al.pdfAccepted author manuscript, 154 KBLicence: CC BY-NC-ND

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title = "Neuronal Cytoskeleton: Presynaptic Boutons as Hotspots for Activity-Dependent Microtubule Nucleation",

abstract = "Local microtubule remodeling plays a crucial role in controlling the transport of neuronal cargo. A new study reveals that excitatory en passant boutons in the axon are hotspots for activity-induced microtubule nucleation and provide tracks for interbouton vesicle trafficking.",

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DO - 10.1016/j.cub.2019.11.011

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JO - Current Biology

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