Next-generation sequencing-based genome diagnostics across clinical genetics centers: implementation choices and their effects

Terry Vrijenhoek; Ken Kraaijeveld; Martin Elferink; Joep de Ligt; Elcke Kranendonk; Gijs Santen; Isaac J Nijman; Derek Butler; Godelieve Claes; Adalberto Costessi; Wim Dorlijn; Winfried van Eyndhoven; Dicky J J Halley; Mirjam C G N van den Hout; Steven van Hove; Lennart F Johansson; Jan D H Jongbloed; Rick Kamps; Christel E M Kockx; Bart de Koning; Marjolein Kriek; Ronald Lekanne Dit Deprez; Hans Lunstroo; Marcel Mannens; Olaf R Mook; Marcel Nelen; Corrette Ploem; Marco Rijnen; Jasper J Saris; Richard Sinke; Erik Sistermans; Marjon van Slegtenhorst; Frank Sleutels; Nienke van der Stoep; Marianne van Tienhoven; Martijn Vermaat; Maartje Vogel; Quinten Waisfisz; Janneke Marjan Weiss; Arthur van den Wijngaard; Wilbert van Workum; Helger Ijntema; Bert van der Zwaag; Wilfred F J van IJcken; Johan T den Dunnen; Joris A Veltman; Raoul Hennekam; Edwin Cuppen

doi:10.1038/ejhg.2015.44

Next-generation sequencing-based genome diagnostics across clinical genetics centers: implementation choices and their effects

Terry Vrijenhoek, Ken Kraaijeveld, Martin Elferink, Joep de Ligt, Elcke Kranendonk, Gijs Santen, Isaac J Nijman, Derek Butler, Godelieve Claes, Adalberto Costessi, Wim Dorlijn, Winfried van Eyndhoven, Dicky J J Halley, Mirjam C G N van den Hout, Steven van Hove, Lennart F Johansson, Jan D H Jongbloed, Rick Kamps, Christel E M Kockx, Bart de KoningMarjolein Kriek, Ronald Lekanne Dit Deprez, Hans Lunstroo, Marcel Mannens, Olaf R Mook, Marcel Nelen, Corrette Ploem, Marco Rijnen, Jasper J Saris, Richard Sinke, Erik Sistermans, Marjon van Slegtenhorst, Frank Sleutels, Nienke van der Stoep, Marianne van Tienhoven, Martijn Vermaat, Maartje Vogel, Quinten Waisfisz, Janneke Marjan Weiss, Arthur van den Wijngaard, Wilbert van Workum, Helger Ijntema, Bert van der Zwaag, Wilfred F J van IJcken, Johan T den Dunnen, Joris A Veltman, Raoul Hennekam, Edwin Cuppen

Hubrecht Institute

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

8 Citations (Scopus)

Original language	English
Pages (from-to)	1270
Journal	European Journal of Human Genetics
Volume	23
Issue number	9
DOIs	https://doi.org/10.1038/ejhg.2015.44
Publication status	Published - Sept 2015

Access to Document

10.1038/ejhg.2015.44

Cite this

Vrijenhoek, T., Kraaijeveld, K., Elferink, M., de Ligt, J., Kranendonk, E., Santen, G., Nijman, I. J., Butler, D., Claes, G., Costessi, A., Dorlijn, W., van Eyndhoven, W., Halley, D. J. J., van den Hout, M. C. G. N., van Hove, S., Johansson, L. F., Jongbloed, J. D. H., Kamps, R., Kockx, C. E. M., ... Cuppen, E. (2015). Next-generation sequencing-based genome diagnostics across clinical genetics centers: implementation choices and their effects. European Journal of Human Genetics, 23(9), 1270. https://doi.org/10.1038/ejhg.2015.44

@article{40adc081998443c7b0e32170c43f20c1,

title = "Next-generation sequencing-based genome diagnostics across clinical genetics centers: implementation choices and their effects",

author = "Terry Vrijenhoek and Ken Kraaijeveld and Martin Elferink and {de Ligt}, Joep and Elcke Kranendonk and Gijs Santen and Nijman, {Isaac J} and Derek Butler and Godelieve Claes and Adalberto Costessi and Wim Dorlijn and {van Eyndhoven}, Winfried and Halley, {Dicky J J} and {van den Hout}, {Mirjam C G N} and {van Hove}, Steven and Johansson, {Lennart F} and Jongbloed, {Jan D H} and Rick Kamps and Kockx, {Christel E M} and {de Koning}, Bart and Marjolein Kriek and Deprez, {Ronald Lekanne Dit} and Hans Lunstroo and Marcel Mannens and Mook, {Olaf R} and Marcel Nelen and Corrette Ploem and Marco Rijnen and Saris, {Jasper J} and Richard Sinke and Erik Sistermans and {van Slegtenhorst}, Marjon and Frank Sleutels and {van der Stoep}, Nienke and {van Tienhoven}, Marianne and Martijn Vermaat and Maartje Vogel and Quinten Waisfisz and Weiss, {Janneke Marjan} and {van den Wijngaard}, Arthur and {van Workum}, Wilbert and Helger Ijntema and {van der Zwaag}, Bert and {van IJcken}, {Wilfred F J} and {den Dunnen}, {Johan T} and Veltman, {Joris A} and Raoul Hennekam and Edwin Cuppen",

year = "2015",

month = sep,

doi = "10.1038/ejhg.2015.44",

language = "English",

volume = "23",

pages = "1270",

journal = "European Journal of Human Genetics",

issn = "1018-4813",

publisher = "Nature Publishing Group",

number = "9",

}

Vrijenhoek, T, Kraaijeveld, K, Elferink, M, de Ligt, J, Kranendonk, E, Santen, G, Nijman, IJ, Butler, D, Claes, G, Costessi, A, Dorlijn, W, van Eyndhoven, W, Halley, DJJ, van den Hout, MCGN, van Hove, S, Johansson, LF, Jongbloed, JDH, Kamps, R, Kockx, CEM, de Koning, B, Kriek, M, Deprez, RLD, Lunstroo, H, Mannens, M, Mook, OR, Nelen, M, Ploem, C, Rijnen, M, Saris, JJ, Sinke, R, Sistermans, E, van Slegtenhorst, M, Sleutels, F, van der Stoep, N, van Tienhoven, M, Vermaat, M, Vogel, M, Waisfisz, Q, Weiss, JM, van den Wijngaard, A, van Workum, W, Ijntema, H, van der Zwaag, B, van IJcken, WFJ, den Dunnen, JT, Veltman, JA, Hennekam, R & Cuppen, E 2015, 'Next-generation sequencing-based genome diagnostics across clinical genetics centers: implementation choices and their effects', European Journal of Human Genetics, vol. 23, no. 9, pp. 1270. https://doi.org/10.1038/ejhg.2015.44

TY - JOUR

T1 - Next-generation sequencing-based genome diagnostics across clinical genetics centers

T2 - implementation choices and their effects

AU - Vrijenhoek, Terry

AU - Kraaijeveld, Ken

AU - Elferink, Martin

AU - de Ligt, Joep

AU - Kranendonk, Elcke

AU - Santen, Gijs

AU - Nijman, Isaac J

AU - Butler, Derek

AU - Claes, Godelieve

AU - Costessi, Adalberto

AU - Dorlijn, Wim

AU - van Eyndhoven, Winfried

AU - Halley, Dicky J J

AU - van den Hout, Mirjam C G N

AU - van Hove, Steven

AU - Johansson, Lennart F

AU - Jongbloed, Jan D H

AU - Kamps, Rick

AU - Kockx, Christel E M

AU - de Koning, Bart

AU - Kriek, Marjolein

AU - Deprez, Ronald Lekanne Dit

AU - Lunstroo, Hans

AU - Mannens, Marcel

AU - Mook, Olaf R

AU - Nelen, Marcel

AU - Ploem, Corrette

AU - Rijnen, Marco

AU - Saris, Jasper J

AU - Sinke, Richard

AU - Sistermans, Erik

AU - van Slegtenhorst, Marjon

AU - Sleutels, Frank

AU - van der Stoep, Nienke

AU - van Tienhoven, Marianne

AU - Vermaat, Martijn

AU - Vogel, Maartje

AU - Waisfisz, Quinten

AU - Weiss, Janneke Marjan

AU - van den Wijngaard, Arthur

AU - van Workum, Wilbert

AU - Ijntema, Helger

AU - van der Zwaag, Bert

AU - van IJcken, Wilfred F J

AU - den Dunnen, Johan T

AU - Veltman, Joris A

AU - Hennekam, Raoul

AU - Cuppen, Edwin

PY - 2015/9

Y1 - 2015/9

U2 - 10.1038/ejhg.2015.44

DO - 10.1038/ejhg.2015.44

M3 - Article

C2 - 26269248

SN - 1018-4813

VL - 23

SP - 1270

JO - European Journal of Human Genetics

JF - European Journal of Human Genetics

IS - 9

ER -