Nigrograna mackinnonii, not Trematosphaeria grisea (syn., Madurella grisea), is the main agent of black grain eumycetoma in Latin America

Sarah A. Ahmed, Gloria M. González, Andrés Tirado-Sánchez, Luis Miguel Moreno-López, Sybren De Hoog, Alexandro Bonifaz

Research output: Contribution to journal/periodicalArticleScientificpeer-review

20 Citations (Scopus)

Abstract

Mycetoma, a chronic and mutilating subcutaneous infection recognized by WHO as a neglected tropical disease, has been reported in over 25 countries in Africa, Asia and South America. In Latin America, Trematosphaeria grisea is assumed to be the prevalent fungal agent. Recent molecular studies have shown that this is an environmental saprobe in Europe where it is rarely implicated in human diseases. The aim of the present paper is to establish the identity of Latin American cases ascribed to Trematosphaeria grisea. Three cases analyzed were caused by Nigrograna mackinnonii. Data on an additional 21 strains in literature revealed that N. mackinnonii rather than T. grisea is responsible for most cases of black grain eumycetoma in Latin America.
Original languageEnglish
JournalJournal of Clinical Microbiology
Volume56
Issue number3
DOIs
Publication statusPublished - 01 Mar 2018

Keywords

  • Black grain
  • Eumycetoma
  • Madurella grisea
  • Mexico
  • Mycetoma
  • Nigrograna mackinnonii
  • Pyrenochaeta mackinnonii
  • Trematosphaeria grisea

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