Objectively measured sleep and body mass index: a prospective bidirectional study in middle-aged and older adults

Chantal M Koolhaas; Desana Kocevska; Bart H W Te Lindert; Nicole S Erler; Oscar H Franco; Annemarie I Luik; Henning Tiemeier

doi:10.1016/j.sleep.2019.01.034

Objectively measured sleep and body mass index: a prospective bidirectional study in middle-aged and older adults

Chantal M Koolhaas, Desana Kocevska, Bart H W Te Lindert, Nicole S Erler, Oscar H Franco, Annemarie I Luik, Henning Tiemeier

Netherlands Institute for Neuroscience (NIN)

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

36 Citations (Scopus)

Abstract

BACKGROUND: In recent years, short sleep has been increasingly recognized as a risk factor for obesity. However, current evidence has so far been limited to cross-sectional studies or longitudinal studies using self-reported sleep. Therefore, we explored the directionality of the association between objectively measured sleep and body mass index (BMI).

METHODS: The study consists of 1031 participants from the general population (52% women, 45-91 years at baseline). Sleep, BMI and waist circumference (WC) were measured twice across a follow-up of six years. BMI and WC were measured at the research center. Total sleep time (TST, hrs), sleep onset latency (SOL, min), sleep efficiency (SE, %) and wake after sleep onset (WASO, min) were estimated by a wrist-worn actigraph. In addition, cross-sectional and longitudinal associations in both directions were explored.

RESULTS: An hour shorter TST was cross-sectionally associated with approximately 0.5 kg/m2 higher BMI. Longitudinally, longer TST and higher SE were associated with lower BMI (βTST = -0.75, 95% CI: -1.08, -0.42; βSE = -0.04, 95% CI: -0.08, -0.01). Conversely, one kg/m2 higher BMI was prospectively associated with 0.02 h shorter TST (95% CI: -0.03, -0.01), and this association was more pronounced over time. Results from analyses with WC were in line with those of BMI.

CONCLUSIONS: This is the first study to explore bidirectionality in the association between objectively measured sleep and BMI in a large population of middle-aged and older adults. Indices of poor sleep were associated with higher and less stable BMI across time. Conversely, a high BMI was associated with a decrease in sleep duration. This confirms that the relation between sleep and body size is bidirectional, and changes in either sleep or BMI are likely to co-occur with changes in health through multiple pathways.

Original language	English
Pages (from-to)	43-50
Number of pages	8
Journal	Sleep Medicine
Volume	57
DOIs	https://doi.org/10.1016/j.sleep.2019.01.034
Publication status	Published - Feb 2019

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10.1016/j.sleep.2019.01.034

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title = "Objectively measured sleep and body mass index: a prospective bidirectional study in middle-aged and older adults",

abstract = "BACKGROUND: In recent years, short sleep has been increasingly recognized as a risk factor for obesity. However, current evidence has so far been limited to cross-sectional studies or longitudinal studies using self-reported sleep. Therefore, we explored the directionality of the association between objectively measured sleep and body mass index (BMI).METHODS: The study consists of 1031 participants from the general population (52% women, 45-91 years at baseline). Sleep, BMI and waist circumference (WC) were measured twice across a follow-up of six years. BMI and WC were measured at the research center. Total sleep time (TST, hrs), sleep onset latency (SOL, min), sleep efficiency (SE, %) and wake after sleep onset (WASO, min) were estimated by a wrist-worn actigraph. In addition, cross-sectional and longitudinal associations in both directions were explored.RESULTS: An hour shorter TST was cross-sectionally associated with approximately 0.5 kg/m2 higher BMI. Longitudinally, longer TST and higher SE were associated with lower BMI (βTST = -0.75, 95% CI: -1.08, -0.42; βSE = -0.04, 95% CI: -0.08, -0.01). Conversely, one kg/m2 higher BMI was prospectively associated with 0.02 h shorter TST (95% CI: -0.03, -0.01), and this association was more pronounced over time. Results from analyses with WC were in line with those of BMI.CONCLUSIONS: This is the first study to explore bidirectionality in the association between objectively measured sleep and BMI in a large population of middle-aged and older adults. Indices of poor sleep were associated with higher and less stable BMI across time. Conversely, a high BMI was associated with a decrease in sleep duration. This confirms that the relation between sleep and body size is bidirectional, and changes in either sleep or BMI are likely to co-occur with changes in health through multiple pathways.",

author = "Koolhaas, {Chantal M} and Desana Kocevska and {Te Lindert}, {Bart H W} and Erler, {Nicole S} and Franco, {Oscar H} and Luik, {Annemarie I} and Henning Tiemeier",

year = "2019",

month = feb,

doi = "10.1016/j.sleep.2019.01.034",

language = "English",

volume = "57",

pages = "43--50",

journal = "Sleep Medicine",

issn = "1389-9457",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - Objectively measured sleep and body mass index

T2 - a prospective bidirectional study in middle-aged and older adults

AU - Koolhaas, Chantal M

AU - Kocevska, Desana

AU - Te Lindert, Bart H W

AU - Erler, Nicole S

AU - Franco, Oscar H

AU - Luik, Annemarie I

AU - Tiemeier, Henning

PY - 2019/2

Y1 - 2019/2

N2 - BACKGROUND: In recent years, short sleep has been increasingly recognized as a risk factor for obesity. However, current evidence has so far been limited to cross-sectional studies or longitudinal studies using self-reported sleep. Therefore, we explored the directionality of the association between objectively measured sleep and body mass index (BMI).METHODS: The study consists of 1031 participants from the general population (52% women, 45-91 years at baseline). Sleep, BMI and waist circumference (WC) were measured twice across a follow-up of six years. BMI and WC were measured at the research center. Total sleep time (TST, hrs), sleep onset latency (SOL, min), sleep efficiency (SE, %) and wake after sleep onset (WASO, min) were estimated by a wrist-worn actigraph. In addition, cross-sectional and longitudinal associations in both directions were explored.RESULTS: An hour shorter TST was cross-sectionally associated with approximately 0.5 kg/m2 higher BMI. Longitudinally, longer TST and higher SE were associated with lower BMI (βTST = -0.75, 95% CI: -1.08, -0.42; βSE = -0.04, 95% CI: -0.08, -0.01). Conversely, one kg/m2 higher BMI was prospectively associated with 0.02 h shorter TST (95% CI: -0.03, -0.01), and this association was more pronounced over time. Results from analyses with WC were in line with those of BMI.CONCLUSIONS: This is the first study to explore bidirectionality in the association between objectively measured sleep and BMI in a large population of middle-aged and older adults. Indices of poor sleep were associated with higher and less stable BMI across time. Conversely, a high BMI was associated with a decrease in sleep duration. This confirms that the relation between sleep and body size is bidirectional, and changes in either sleep or BMI are likely to co-occur with changes in health through multiple pathways.

AB - BACKGROUND: In recent years, short sleep has been increasingly recognized as a risk factor for obesity. However, current evidence has so far been limited to cross-sectional studies or longitudinal studies using self-reported sleep. Therefore, we explored the directionality of the association between objectively measured sleep and body mass index (BMI).METHODS: The study consists of 1031 participants from the general population (52% women, 45-91 years at baseline). Sleep, BMI and waist circumference (WC) were measured twice across a follow-up of six years. BMI and WC were measured at the research center. Total sleep time (TST, hrs), sleep onset latency (SOL, min), sleep efficiency (SE, %) and wake after sleep onset (WASO, min) were estimated by a wrist-worn actigraph. In addition, cross-sectional and longitudinal associations in both directions were explored.RESULTS: An hour shorter TST was cross-sectionally associated with approximately 0.5 kg/m2 higher BMI. Longitudinally, longer TST and higher SE were associated with lower BMI (βTST = -0.75, 95% CI: -1.08, -0.42; βSE = -0.04, 95% CI: -0.08, -0.01). Conversely, one kg/m2 higher BMI was prospectively associated with 0.02 h shorter TST (95% CI: -0.03, -0.01), and this association was more pronounced over time. Results from analyses with WC were in line with those of BMI.CONCLUSIONS: This is the first study to explore bidirectionality in the association between objectively measured sleep and BMI in a large population of middle-aged and older adults. Indices of poor sleep were associated with higher and less stable BMI across time. Conversely, a high BMI was associated with a decrease in sleep duration. This confirms that the relation between sleep and body size is bidirectional, and changes in either sleep or BMI are likely to co-occur with changes in health through multiple pathways.

U2 - 10.1016/j.sleep.2019.01.034

DO - 10.1016/j.sleep.2019.01.034

M3 - Article

C2 - 30897455

SN - 1389-9457

VL - 57

SP - 43

EP - 50

JO - Sleep Medicine

JF - Sleep Medicine

ER -

Objectively measured sleep and body mass index: a prospective bidirectional study in middle-aged and older adults

Abstract

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