(Post-)genomics approaches in fungal research

María Victoria Aguilar-Pontes, Ronald P de Vries, M. Zhou, J. van den Brink

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

    Abstract

    To date, hundreds of fungal genomes have been sequenced and many more are in progress. This wealth of genomic information has provided new directions to study fungal biodiversity. However, to further dissect and understand the complicated biological mechanisms involved in fungal life styles, functional studies beyond genomes are required. Thanks to the developments of current -omics techniques, it is possible to produce large amounts of fungal functional data in a high-throughput fashion (e.g. transcriptome, proteome, etc.). The increasing ease of creating -omics data has also created a major challenge for downstream data handling and analysis. Numerous databases, tools and software have been created to meet this challenge. Facing such a richness of techniques and information, hereby we provide a brief roadmap on current wet-lab and bioinformatics approaches to study functional genomics in fungi.

    Original languageEnglish
    Pages (from-to)424-39
    Number of pages16
    JournalBriefings in Functional Genomics
    Volume13
    Issue number6
    DOIs
    Publication statusPublished - Nov 2014

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