Potent Activities of Luliconazole, Lanoconazole, and Eight Comparators against Molecularly Characterized Fusarium Species

Mahdi Abastabar; Abdullah M.S. Al-Hatmi; Mohammad Vafaei Moghaddam; G. Sybren De Hoog; Iman Haghani; Seyed Reza Aghili; Tahereh Shokohi; Mohammad Taghi Hedayati; Roshanak Daie Ghazvini; Reza Kachuei; Ali Rezaei-Matehkolaei; Koichi Makimura; Jacques F. Meis; Hamid Badalia

doi:10.1128/AAC.00009-18

Potent Activities of Luliconazole, Lanoconazole, and Eight Comparators against Molecularly Characterized Fusarium Species

Mahdi Abastabar, Abdullah M.S. Al-Hatmi, Mohammad Vafaei Moghaddam, G. Sybren De Hoog, Iman Haghani, Seyed Reza Aghili, Tahereh Shokohi, Mohammad Taghi Hedayati, Roshanak Daie Ghazvini, Reza Kachuei, Ali Rezaei-Matehkolaei, Koichi Makimura, Jacques F. Meis, Hamid Badalia

Research output: Chapter in book/volume › Chapter › Scientific › peer-review

27 Citations (Scopus)

Abstract

Copyright © 2018 American Society for Microbiology. All Rights Reserved. A collection of clinical (n 47) and environmental (n 79) Fusarium isolates were tested against 10 antifungal drugs, including 2 novel imidazoles. Luliconazole and lanoconazole demonstrated very low geometric mean MIC values of 0.005 and 0.013 g/ml, respectively, compared with 0.51 g/ml for micafungin, 0.85 g/ml for efinaconazole, 1.12 g/ml for natamycin, 1.18 g/ml for anidulafungin, 1.31 g/ml for voriconazole, 1.35 g/ml for caspofungin, 1.9 g/ml for amphotericin B, and 4.08 g/ml for itraconazole. Results show that these drugs are potential candidates for (topical) treatment of skin and nail infections due to Fusarium species.

Original language	English
Title of host publication	Antimicrobial Agents and Chemotherapy
Publisher	American Society for Microbiology
ISBN (Print)	0066-4804
DOIs	https://doi.org/10.1128/AAC.00009-18
Publication status	Published - 01 May 2018

Publication series

Name	Antimicrobial Agents and Chemotherapy
Volume	62

Keywords

Fusarium species
Intrinsic resistance
Lanoconazole
Luliconazole

Access to Document

10.1128/AAC.00009-18

http://www.mendeley.com/research/potent-activities-luliconazole-lanoconazole-eight-comparators-against-molecularly-characterized-fusa

Cite this

Abastabar, M., Al-Hatmi, A. M. S., Moghaddam, M. V., De Hoog, G. S., Haghani, I., Aghili, S. R., Shokohi, T., Hedayati, M. T., Ghazvini, R. D., Kachuei, R., Rezaei-Matehkolaei, A., Makimura, K., Meis, J. F., & Badalia, H. (2018). Potent Activities of Luliconazole, Lanoconazole, and Eight Comparators against Molecularly Characterized Fusarium Species. In Antimicrobial Agents and Chemotherapy (Antimicrobial Agents and Chemotherapy; Vol. 62). American Society for Microbiology. https://doi.org/10.1128/AAC.00009-18

@inbook{d42c8ae1b22745b4a0e818c784bc44e0,

title = "Potent Activities of Luliconazole, Lanoconazole, and Eight Comparators against Molecularly Characterized Fusarium Species",

abstract = "Copyright {\textcopyright} 2018 American Society for Microbiology. All Rights Reserved. A collection of clinical (n 47) and environmental (n 79) Fusarium isolates were tested against 10 antifungal drugs, including 2 novel imidazoles. Luliconazole and lanoconazole demonstrated very low geometric mean MIC values of 0.005 and 0.013 g/ml, respectively, compared with 0.51 g/ml for micafungin, 0.85 g/ml for efinaconazole, 1.12 g/ml for natamycin, 1.18 g/ml for anidulafungin, 1.31 g/ml for voriconazole, 1.35 g/ml for caspofungin, 1.9 g/ml for amphotericin B, and 4.08 g/ml for itraconazole. Results show that these drugs are potential candidates for (topical) treatment of skin and nail infections due to Fusarium species.",

keywords = "Fusarium species, Intrinsic resistance, Lanoconazole, Luliconazole",

author = "Mahdi Abastabar and Al-Hatmi, {Abdullah M.S.} and Moghaddam, {Mohammad Vafaei} and {De Hoog}, {G. Sybren} and Iman Haghani and Aghili, {Seyed Reza} and Tahereh Shokohi and Hedayati, {Mohammad Taghi} and Ghazvini, {Roshanak Daie} and Reza Kachuei and Ali Rezaei-Matehkolaei and Koichi Makimura and Meis, {Jacques F.} and Hamid Badalia",

year = "2018",

month = may,

day = "1",

doi = "10.1128/AAC.00009-18",

language = "English",

isbn = "0066-4804",

series = "Antimicrobial Agents and Chemotherapy",

publisher = "American Society for Microbiology",

booktitle = "Antimicrobial Agents and Chemotherapy",

address = "United States",

}

Abastabar, M, Al-Hatmi, AMS, Moghaddam, MV, De Hoog, GS, Haghani, I, Aghili, SR, Shokohi, T, Hedayati, MT, Ghazvini, RD, Kachuei, R, Rezaei-Matehkolaei, A, Makimura, K, Meis, JF & Badalia, H 2018, Potent Activities of Luliconazole, Lanoconazole, and Eight Comparators against Molecularly Characterized Fusarium Species. in Antimicrobial Agents and Chemotherapy. Antimicrobial Agents and Chemotherapy, vol. 62, American Society for Microbiology. https://doi.org/10.1128/AAC.00009-18

Potent Activities of Luliconazole, Lanoconazole, and Eight Comparators against Molecularly Characterized Fusarium Species. / Abastabar, Mahdi; Al-Hatmi, Abdullah M.S.; Moghaddam, Mohammad Vafaei et al.
Antimicrobial Agents and Chemotherapy. American Society for Microbiology, 2018. (Antimicrobial Agents and Chemotherapy; Vol. 62).

Research output: Chapter in book/volume › Chapter › Scientific › peer-review

TY - CHAP

T1 - Potent Activities of Luliconazole, Lanoconazole, and Eight Comparators against Molecularly Characterized Fusarium Species

AU - Abastabar, Mahdi

AU - Al-Hatmi, Abdullah M.S.

AU - Moghaddam, Mohammad Vafaei

AU - De Hoog, G. Sybren

AU - Haghani, Iman

AU - Aghili, Seyed Reza

AU - Shokohi, Tahereh

AU - Hedayati, Mohammad Taghi

AU - Ghazvini, Roshanak Daie

AU - Kachuei, Reza

AU - Rezaei-Matehkolaei, Ali

AU - Makimura, Koichi

AU - Meis, Jacques F.

AU - Badalia, Hamid

PY - 2018/5/1

Y1 - 2018/5/1

N2 - Copyright © 2018 American Society for Microbiology. All Rights Reserved. A collection of clinical (n 47) and environmental (n 79) Fusarium isolates were tested against 10 antifungal drugs, including 2 novel imidazoles. Luliconazole and lanoconazole demonstrated very low geometric mean MIC values of 0.005 and 0.013 g/ml, respectively, compared with 0.51 g/ml for micafungin, 0.85 g/ml for efinaconazole, 1.12 g/ml for natamycin, 1.18 g/ml for anidulafungin, 1.31 g/ml for voriconazole, 1.35 g/ml for caspofungin, 1.9 g/ml for amphotericin B, and 4.08 g/ml for itraconazole. Results show that these drugs are potential candidates for (topical) treatment of skin and nail infections due to Fusarium species.

AB - Copyright © 2018 American Society for Microbiology. All Rights Reserved. A collection of clinical (n 47) and environmental (n 79) Fusarium isolates were tested against 10 antifungal drugs, including 2 novel imidazoles. Luliconazole and lanoconazole demonstrated very low geometric mean MIC values of 0.005 and 0.013 g/ml, respectively, compared with 0.51 g/ml for micafungin, 0.85 g/ml for efinaconazole, 1.12 g/ml for natamycin, 1.18 g/ml for anidulafungin, 1.31 g/ml for voriconazole, 1.35 g/ml for caspofungin, 1.9 g/ml for amphotericin B, and 4.08 g/ml for itraconazole. Results show that these drugs are potential candidates for (topical) treatment of skin and nail infections due to Fusarium species.

KW - Fusarium species

KW - Intrinsic resistance

KW - Lanoconazole

KW - Luliconazole

U2 - 10.1128/AAC.00009-18

DO - 10.1128/AAC.00009-18

M3 - Chapter

C2 - 29530844

SN - 0066-4804

T3 - Antimicrobial Agents and Chemotherapy

BT - Antimicrobial Agents and Chemotherapy

PB - American Society for Microbiology

ER -

Potent Activities of Luliconazole, Lanoconazole, and Eight Comparators against Molecularly Characterized Fusarium Species

Abstract

Publication series

Keywords

Access to Document

Fingerprint

Cite this