Primed to perish: heightened mitochondrial priming explains hESC apoptosis sensitivity

N. Geijsen

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Abstract

Human embryonic stem cells (hESCs) are hypersensitive to apoptotic stimuli, though the underlying mechanisms are poorly characterized. In this issue of Cell Stem Cell, Liu et al. (2013) report that mitochondria of human ESCs exist in an apoptosis-prone state, ready to act as cellular executioners upon detecting DNA damage.
Original languageEnglish
Pages (from-to)371-372
JournalCell Stem Cell
Volume13
Issue number4
DOIs
Publication statusPublished - 2013

Fingerprint

Dive into the research topics of 'Primed to perish: heightened mitochondrial priming explains hESC apoptosis sensitivity'. Together they form a unique fingerprint.

Cite this