PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation
- Lok Hei Chan
- , Lei Zhou
- , Kai Yu Ng
- , Tin Lok Wong
- , Terence K Lee
- , Rakesh Sharma
- , Jane H Loong
- , Yick Pang Ching
- , Yun-Fei Yuan
- , Dan Xie
- , Chung Mau Lo
- , Kwan Man
- , Benedetta Artegiani
- , Hans Clevers
- , Helen H Yan
- , Suet Yi Leung
- , Stéphane Richard
- , Xin-Yuan Guan
- , Michael S Y Huen
- , Stephanie Ma
- School of Biomedical Sciences, University of Hong Kong, Pokfulam, Hong Kong, China.
- Department of Applied Biology & Chemical Technology, Hong Kong Polytechnic University, Hong Kong, China.
- Proteomics & Metabolomics Core Facility, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, China.
- School of Biomedical Sciences, University of Hong Kong, Pokfulam, Hong Kong, China; State Key Laboratory for Liver Research, University of Hong Kong, Pokfulam, Hong Kong, China.
- State Key Laboratory of Oncology in Southern China, Sun Yat-Sen University Cancer Centre, Guangzhou, China.
- State Key Laboratory for Liver Research, University of Hong Kong, Pokfulam, Hong Kong, China; Department of Surgery, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, China.
- Hubrecht Institute for Developmental Biology and Stem Cell Research, University Medical Centre Utrecht, Utrecht, The Netherlands.
- Department of Pathology, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, China.
- Lady Davis Institute, Jewish General Hospital, and Departments of Oncology and Medicine, McGill University, Montreal, QC, Canada.
- State Key Laboratory for Liver Research, University of Hong Kong, Pokfulam, Hong Kong, China; Department of Clinical Oncology, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, China.
- School of Biomedical Sciences, University of Hong Kong, Pokfulam, Hong Kong, China; State Key Laboratory for Liver Research, University of Hong Kong, Pokfulam, Hong Kong, China. Electronic address: [email protected].
Research output: Contribution to journal/periodical › Article › Scientific › peer-review
100
Citations
(Scopus)