Prospective evaluation of the chromogenic medium CandiSelect 4 for differentiation and presumptive identification of non-Candida albicans Candida species

Liang Zhao, G Sybren de Hoog, Akke Cornelissen, Qian Lyu, Lili Mou, Taohua Liu, Yu Cao, Mansoureh Vatanshenassan, Yingqian Kang

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

    6 Citations (Scopus)

    Abstract

    Rapid identification of pathogenic yeasts is a crucial step in timely and appropriate antifungal therapy. For diagnostics in the clinical laboratory, simplified alternatives to barcoding are needed. CandiSelect 4 (CS4) medium, a chromogenic medium for isolation of clinical yeasts, allows routine recognition of Candida albicans and presumptive identification of Candida tropicalis, Candida glabrata, and Candida krusei. We evaluated an extension of this method with 46 non-Candida albicans Candida (NCAC) and 7 Malassezia species. The medium supported growth of all species tested and a wide diversity of cultural types were observed. Colony colours were in violet, turquoise (including green and blue), or white tinges. Eight NCAC species produced violet pigmentation similar to that of C. albicans. Most NCAC species, including C. glabrata and C. tropicalis were distributed in the turquoise group. Malassezia species were invariably blue.

    Original languageEnglish
    Pages (from-to)173-8
    Number of pages6
    JournalFungal Biology
    Volume120
    Issue number2
    DOIs
    Publication statusPublished - Feb 2016

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