Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns

Yannik Bollen, Ellen Stelloo, Petra van Leenen, Myrna van den Bos, Bas Ponsioen, Bingxin Lu, Markus J van Roosmalen, Ana C F Bolhaqueiro, Christopher Kimberley, Maximilian Mossner, William C H Cross, Nicolle J M Besselink, Bastiaan van der Roest, Sander Boymans, Koen C Oost, Sippe G de Vries, Holger Rehmann, Edwin Cuppen, Susanne M A Lens, Geert J P L KopsWigard P Kloosterman, Leon W M M Terstappen, Chris P Barnes, Andrea Sottoriva, Trevor A Graham, Hugo J G Snippert

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Medicine & Life Sciences