Retriever fetches integrins from endosomes

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Abstract

Recycling from endosomes to the plasma membrane is an important step in cell homeostasis. The retromer/SNX27/WASH complex recycles numerous receptors, but key ones are still unaccounted for. Now a related conserved heterotrimer, called retriever, has been identified that, together with SNX17, the CCC complex and WASH, mediates the recycling of α5β1 integrins.

Original languageEnglish
Pages (from-to)1144-1146
Number of pages3
JournalNature Cell Biology
Volume19
Issue number10
DOIs
Publication statusPublished - 29 Sep 2017

Keywords

  • Cell Membrane
  • Endosomes
  • Humans
  • Integrins
  • Protein Transport
  • Sorting Nexins
  • Journal Article

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