Recycling from endosomes to the plasma membrane is an important step in cell homeostasis. The retromer/SNX27/WASH complex recycles numerous receptors, but key ones are still unaccounted for. Now a related conserved heterotrimer, called retriever, has been identified that, together with SNX17, the CCC complex and WASH, mediates the recycling of α5β1 integrins.

Original languageEnglish
Pages (from-to)1144-1146
Number of pages3
JournalNature Cell Biology
Issue number10
StatePublished - 29 Sep 2017

    Research areas

  • Cell Membrane, Endosomes, Humans, Integrins, Protein Transport, Sorting Nexins, Journal Article

ID: 6033653