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  • 6302_Baugh et al_2017__Hormones&Behavior_POST_PRINT

    Accepted author manuscript, 315 KB, PDF-document

    Embargo ends: 22/05/2018

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  • 6302_Baugh

    Final published version, 555 KB, PDF-document

DOI

  • A.T. Baugh
  • R.A. Senft
  • M. Firke
  • A. Lauder
  • J. Schroeder
  • S.L. Meddle
  • K. van Oers
  • Michaela Hau
Hormonal pleiotropy—the simultaneous influence of a single hormone on multiple traits—has been hypothesized as an important mechanism underlying personality, and circulating glucocorticoids are central to this idea. A major gap in our understanding is the neural basis for this link. Here we examine the stability and structure of behavioral, endocrine and neuroendocrine traits in a population of songbirds (Parus major). Upon identifying stable and covarying behavioral and endocrine traits, we test the hypothesis that risk-averse personalities exhibit a neuroendocrine stress axis that is systemically potentiated—characterized by stronger glucocorticoid reactivity and weaker negative feedback. We show high among-individual variation and covariation (i.e. personality) in risk-taking behaviors and demonstrate that four aspects of glucocorticoid physiology (baseline, stress response, negative feedback strength and adrenal sensitivity) are also repeatable and covary. Further, we establish that high expression of mineralocorticoid and low expression of glucocorticoid receptor in the brain are linked with systemically elevated plasma glucocorticoid levels and more risk-averse personalities. Our findings support the hypothesis that steroid hormones can exert pleiotropic effects that organize behavioral phenotypes and provide novel evidence that neuroendocrine factors robustly explain a large fraction of endocrine and personality variation.
Original languageEnglish
Pages (from-to)99-108
JournalHormones and Behavior
Volume93
Issue numberJuly
DOI
StatePublished - 2017

    Research areas

  • international

ID: 4251631