Single nucleotide polymorphism (SNP) panels for rapid positional cloning in zebrafish

TY - JOUR

T1 - Single nucleotide polymorphism (SNP) panels for rapid positional cloning in zebrafish

AU - Clark, M.D.

AU - Guryev, V.

AU - de Bruijn, E.

AU - Nijman, I.J.

AU - Tada, M.

AU - Wilson, C.

AU - Deloukas, P.

AU - Postlethwait, J.H.

AU - Cuppen, E.

AU - Stemple, D.L.

N1 - Reporting year: 2011

PY - 2011

Y1 - 2011

N2 - Despite considerable genetic and genomic resources the positional cloning of forward mutations remains a slow and manually intensive task, typically using gel based genotyping and sequential rounds of mapping. We have used the latest genetic resources and genotyping technologies to develop two commercially available SNP panels of thousands of markers that can be used to speed up positional cloning.

AB - Despite considerable genetic and genomic resources the positional cloning of forward mutations remains a slow and manually intensive task, typically using gel based genotyping and sequential rounds of mapping. We have used the latest genetic resources and genotyping technologies to develop two commercially available SNP panels of thousands of markers that can be used to speed up positional cloning.

U2 - 10.1016/B978-0-12-374814-0.00013-6

DO - 10.1016/B978-0-12-374814-0.00013-6

M3 - Article

SN - 0091-679X

VL - 104

SP - 219

EP - 235

JO - Methods in Cell Biology

JF - Methods in Cell Biology

ER -