SnapShot: Growing Organoids from Stem Cells

Toshiro Sato, Hans Clevers

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Abstract

Tissue stem cells require unique niche microenvironments. In the presence of specific combinations of niche factors, mouse and human epithelial tissues from stomach, small intestine, colon, pancreas duct, and liver bile duct efficiently form stereotypic organoids. The platform of epitheloid organoids can also be employed for in vitro generation of digestive tissue from human pluripotent stem cells. Organoids hold great promise for basic and translational research.

Original languageEnglish
Pages (from-to)1700-1700.e1
JournalCell
Volume161
Issue number7
DOIs
Publication statusPublished - 18 Jun 2015

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