SnapShot: Growing Organoids from Stem Cells

Toshiro Sato; Hans Clevers

doi:10.1016/j.cell.2015.06.028

SnapShot: Growing Organoids from Stem Cells

Toshiro Sato, Hans Clevers

Hubrecht Institute

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

117 Citations (Scopus)

Abstract

Tissue stem cells require unique niche microenvironments. In the presence of specific combinations of niche factors, mouse and human epithelial tissues from stomach, small intestine, colon, pancreas duct, and liver bile duct efficiently form stereotypic organoids. The platform of epitheloid organoids can also be employed for in vitro generation of digestive tissue from human pluripotent stem cells. Organoids hold great promise for basic and translational research.

Original language	English
Pages (from-to)	1700-1700.e1
Journal	Cell
Volume	161
Issue number	7
DOIs	https://doi.org/10.1016/j.cell.2015.06.028
Publication status	Published - 18 Jun 2015

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10.1016/j.cell.2015.06.028

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title = "SnapShot: Growing Organoids from Stem Cells",

abstract = "Tissue stem cells require unique niche microenvironments. In the presence of specific combinations of niche factors, mouse and human epithelial tissues from stomach, small intestine, colon, pancreas duct, and liver bile duct efficiently form stereotypic organoids. The platform of epitheloid organoids can also be employed for in vitro generation of digestive tissue from human pluripotent stem cells. Organoids hold great promise for basic and translational research.",

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AU - Clevers, Hans

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JO - Cell

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SnapShot: Growing Organoids from Stem Cells

Abstract

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