Subcutaneous infection by Ochroconis mirabilis in an immunocompetent patient

Dongmei Shi, Guixia Lu, Huan Mei, G Sybren de Hoog, Kittipan Samerpitak, Shuwen Deng, Yongnian Shen, Weida Liu

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

    Abstract

    Recently, the taxonomy of Ochroconis (Ascomycota, Pezizomycotina, Venturiales, Sympoventuriaceae) has been revised with the recognition of an additional genus, Verruconis. Ochroconis comprises mesophilic saprobes that occasionally infect vertebrates which mostly are cold-blooded, while Verruconis contains thermophilic species which is a neurotrope in humans and birds. On the basis of molecular data it is noted that only a single Ochroconis species regularly infects immunocompetent human hosts. Here we report a subcutaneous infection due to Ochroconis mirabilis in a 50-year-old immunocompetent female patient. In vitro antifungal susceptibility tests revealed that terbinafine was the most effective drug. The patient was successfully cured with oral administration of terbinafine 250 mg daily in combination with 3 times of topical ALA-photodynamic therapy for 9 months.

    Original languageEnglish
    Pages (from-to)44-47
    Number of pages4
    JournalMedical Mycology Case Reports
    Volume11
    DOIs
    Publication statusPublished - Mar 2016

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