Subcutaneous phaeohyphomycosis caused by Exophiala equina, with susceptibility to eight antifungal drugs

M.J. Najafzadeh, M.K. Suh, M.H. Lee, G.Y. Ha, J.R. Kim, T.H. Kim, H.J. Lee, J.S. Choi, J.F.G.M. Meis, G.S. de Hoog

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

    21 Citations (Scopus)

    Abstract

    A case of subcutaneous phaeohyphomycosis caused by Exophiala equina is reported in a 75-year-old female, who showed subcutaneous abscesses on both forearms for 8 months. A lesion was initiated by inoculation with a spine from a tree. Histopathologically, suppurative granulomatous inflammation was present and short hyphal elements were observed. Upon culture greyish-black, velvety colonies of a black yeast were obtained after 3 weeks. The strain grew well at 25 degrees C, but poorly at 37 degrees C. After sequencing the internal transcribed spacer domain and the partial beta-tubulin gene, the fungus was identified as E. equina. The patient was successfully treated with fluconazole for 3 months.
    Original languageEnglish
    Pages (from-to)797-800
    JournalJournal of Medical Microbiology
    Volume62
    Issue numberPt 5
    DOIs
    Publication statusPublished - 2013

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