Successful treatment of chromoblastomycosis of 36 years duration caused by Fonsecaea monophora

M.J. Najafzadeh, A. Rezusta, M.I. Cameo, M.L. Zubiri, M.C. Yus, H. Badali, M.J. Revillo, G.S. de Hoog

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

    Abstract

    We report a case of chromoblastomycosis in a 67-year-old female farmer, which involved a large (20 x 30 cm) cicatricial erythematous plaque on the inner side of her right thigh. The lesion was initially a small nodule which gradually extended over 36 years. Direct microscopic examination revealed a granulomatous lesion with muriform cells surrounded by giant cells. The mould recovered in cultures was dark olivaceous and identified as Fonsecaea monophora by ribosomal internal transcribe spacer (ITS) sequence data. The lesion was successfully cured after 4 months treatment with itraconazole, but there was a relapse.
    Original languageEnglish
    Pages (from-to)390-393
    JournalMedical Mycology
    Volume48
    Issue number2
    DOIs
    Publication statusPublished - 2010

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