Successful treatment of Cryptococcus gattii neurocryptococcosis in a 5-year-old immunocompetent child from the French Guiana Amazon region

Anne Debourgogne, Ferry Hagen, Narcisse Elenga, Laurence Long, Denis Blanchet, Vincent Veron, Olivier Lortholary, Bernard Carme, Christine Aznar

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Abstract

Compared to the incidence in adults, cryptococcosis is rare among children. We report a case of neurocryptococcosis due to Cryptococcus gattii in a five-year-old girl without identified risk factors living in French Guiana. Neurological surgery in combination with long-term antifungal treatment with amphotericin B and 5-flucytosine successfully resolved the cryptococcal infection. Subsequent molecular characterization of the Cryptococcus isolate revealed that the infection was caused by a C. gattii genotype AFLP6B/VGIIb strain.

Original languageEnglish
Pages (from-to)210-3
Number of pages4
JournalRevista Iberoamericana de Micologia
Volume29
Issue number4
DOIs
Publication statusPublished - 01 Mar 2012

Keywords

  • Central Nervous System Fungal Infections/therapy
  • Child, Preschool
  • Cryptococcosis/therapy
  • Cryptococcus gattii
  • Female
  • French Guiana
  • Humans
  • Remission Induction

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