Tales of the unexpected: tcf1 functions as a tumor suppressor for leukemias

F.J. Staal; H. Clevers

doi:10.1016/j.immuni.2012.10.008

Tales of the unexpected: tcf1 functions as a tumor suppressor for leukemias

F.J. Staal, H. Clevers

Hubrecht Institute

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

8 Citations (Scopus)

Abstract

The Wnt-responsive transcription factors Tcf1 and Lef1 are well-known for their roles in lymphocyte development. In this issue of Immunity, Yu et al. (2012) report that Tcf1-deficient mice develop aggressive T cell lymphomas that are characterized by high Lef1 expression.

Original language	English
Pages (from-to)	761-763
Journal	Immunity
Volume	37
Issue number	5
DOIs	https://doi.org/10.1016/j.immuni.2012.10.008
Publication status	Published - 2012

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10.1016/j.immuni.2012.10.008

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title = "Tales of the unexpected: tcf1 functions as a tumor suppressor for leukemias",

abstract = "The Wnt-responsive transcription factors Tcf1 and Lef1 are well-known for their roles in lymphocyte development. In this issue of Immunity, Yu et al. (2012) report that Tcf1-deficient mice develop aggressive T cell lymphomas that are characterized by high Lef1 expression.",

author = "F.J. Staal and H. Clevers",

note = "Reporting year: 2012",

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AU - Clevers, H.

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AB - The Wnt-responsive transcription factors Tcf1 and Lef1 are well-known for their roles in lymphocyte development. In this issue of Immunity, Yu et al. (2012) report that Tcf1-deficient mice develop aggressive T cell lymphomas that are characterized by high Lef1 expression.

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DO - 10.1016/j.immuni.2012.10.008

M3 - Article

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VL - 37

SP - 761

EP - 763

JO - Immunity

JF - Immunity

IS - 5

ER -

Tales of the unexpected: tcf1 functions as a tumor suppressor for leukemias

Abstract

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