Target-selected mutagenesis of the rat

B.M. Smits; J.B. Mudde; R. Plasterk; E. Cuppen

doi:10.1016/j.ygeno.2003.08.010

Target-selected mutagenesis of the rat

B.M. Smits, J.B. Mudde, R. Plasterk, E. Cuppen

Hubrecht Institute

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

68 Citations (Scopus)

Abstract

The rat is one of the most extensively studied model organisms, and with its genome being sequenced, tools to manipulate gene function in vivo have become increasingly important. We here report proof of principle for target-selected mutagenesis as a reverse genetic or knockout approach for the rat.

Original language	English
Pages (from-to)	332-334
Journal	Genomics
Volume	83
Issue number	2
DOIs	https://doi.org/10.1016/j.ygeno.2003.08.010
Publication status	Published - 2004

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10.1016/j.ygeno.2003.08.010

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title = "Target-selected mutagenesis of the rat",

abstract = "The rat is one of the most extensively studied model organisms, and with its genome being sequenced, tools to manipulate gene function in vivo have become increasingly important. We here report proof of principle for target-selected mutagenesis as a reverse genetic or knockout approach for the rat.",

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Target-selected mutagenesis of the rat

Abstract

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