The cancer stem cell: premises, promises and challenges

H. Clevers

doi:10.1038/nm.2304

The cancer stem cell: premises, promises and challenges

H. Clevers

Hubrecht Institute

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

1651 Citations (Scopus)

Abstract

Over the last decade, the notion that tumors are maintained by their own stem cells, the so-called cancer stem cells, has created great excitement in the research community. This review attempts to summarize the underlying concepts of this notion, to distinguish hard facts from beliefs and to define the future challenges of the field.

Original language	English
Pages (from-to)	313-319
Journal	Nature Medicine
Volume	17
Issue number	3
DOIs	https://doi.org/10.1038/nm.2304
Publication status	Published - 2011

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10.1038/nm.2304

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title = "The cancer stem cell: premises, promises and challenges",

abstract = "Over the last decade, the notion that tumors are maintained by their own stem cells, the so-called cancer stem cells, has created great excitement in the research community. This review attempts to summarize the underlying concepts of this notion, to distinguish hard facts from beliefs and to define the future challenges of the field.",

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The cancer stem cell: premises, promises and challenges

Abstract

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