Tissue-Engineering the Intestine: The Trials before the Trials

Hans Clevers; Ryan K Conder; Vivian S W Li; Matthias P Lutolf; Ludovic Vallier; Sarah Chan; Tracy C Grikscheit; Kim B Jensen; Paolo De Coppi

doi:10.1016/j.stem.2019.04.018

Tissue-Engineering the Intestine: The Trials before the Trials

Hans Clevers, Ryan K Conder, Vivian S W Li, Matthias P Lutolf, Ludovic Vallier, Sarah Chan, Tracy C Grikscheit, Kim B Jensen, Paolo De Coppi

Hubrecht Institute

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

38 Citations (Scopus)

Abstract

Building complex tissues requires the development of innovative interdisciplinary engineering solutions. In this Forum, the INTENS Consortium discuss experimental considerations and challenges for generating a tissue-engineered intestine for the treatment of short bowel syndrome, taking into account cell source, scaffold choice, and design strategy for achieving proper assembly and function.

Original language	English
Pages (from-to)	855-859
Number of pages	5
Journal	Cell Stem Cell
Volume	24
Issue number	6
DOIs	https://doi.org/10.1016/j.stem.2019.04.018
Publication status	Published - 06 Jun 2019

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10.1016/j.stem.2019.04.018

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title = "Tissue-Engineering the Intestine: The Trials before the Trials",

abstract = "Building complex tissues requires the development of innovative interdisciplinary engineering solutions. In this Forum, the INTENS Consortium discuss experimental considerations and challenges for generating a tissue-engineered intestine for the treatment of short bowel syndrome, taking into account cell source, scaffold choice, and design strategy for achieving proper assembly and function.",

author = "Hans Clevers and Conder, {Ryan K} and Li, {Vivian S W} and Lutolf, {Matthias P} and Ludovic Vallier and Sarah Chan and Grikscheit, {Tracy C} and Jensen, {Kim B} and {De Coppi}, Paolo",

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AU - Clevers, Hans

AU - Conder, Ryan K

AU - Li, Vivian S W

AU - Lutolf, Matthias P

AU - Vallier, Ludovic

AU - Chan, Sarah

AU - Grikscheit, Tracy C

AU - Jensen, Kim B

AU - De Coppi, Paolo

PY - 2019/6/6

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N2 - Building complex tissues requires the development of innovative interdisciplinary engineering solutions. In this Forum, the INTENS Consortium discuss experimental considerations and challenges for generating a tissue-engineered intestine for the treatment of short bowel syndrome, taking into account cell source, scaffold choice, and design strategy for achieving proper assembly and function.

AB - Building complex tissues requires the development of innovative interdisciplinary engineering solutions. In this Forum, the INTENS Consortium discuss experimental considerations and challenges for generating a tissue-engineered intestine for the treatment of short bowel syndrome, taking into account cell source, scaffold choice, and design strategy for achieving proper assembly and function.

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DO - 10.1016/j.stem.2019.04.018

M3 - Article

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EP - 859

JO - Cell Stem Cell

JF - Cell Stem Cell

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Tissue-Engineering the Intestine: The Trials before the Trials

Abstract

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