Uncertainties in ecological, chemical and physiological parameters of a bioaccumulation model: implications for internal concentrations and tissue based risk quotients

F. De Laender, D.J. Van Oevelen, J.J. Middelburg, K.E.R. Soetaert

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

    Abstract

    Bioaccumulationmodelspredictinternalcontaminantconcentrations(ci) usingecological,chemical and physiologicalparameters.Hereweanalysetheeffectofuncertaintiesontheseparameterson bioaccumulationmodelpredictions.Simultaneouslyconsideringtheuncertaintiesonallthese parametersinabioaccumulationmodelresultedinuncertaintyrangesof ci that increasedwiththe octanolwaterpartitioncoefficient Kow and reachedmaximaofupto1.25logunitsformesozooplankton and upto1.45logunitsfishatlog Kow=8.Aglobalsensitivityanalysis(SA)wasperformedtorankthe contributionofdifferentparameterstotheobserveduncertainty.TheSAdemonstratedthatthis interspeciesdifferenceresultedpredominantlyfromuncertainproductionratesoffish.The Kow, the water concentrationandorganiccarbon–octanolproportionalityconstantwereimportantdriversof uncertaintyon ci for bothspecies.Atissuebasedriskquotient(RQtissue) combininguncertaintyon ci with realistictissuebasedeffectthresholdsindicatedthatfishwereupto10timesmoreprobableto have RQtissue41 thanmesozooplankton,dependingontheconsideredthresholdvalue.Conventional exposurebasedriskquotientswereupto5timeslessprobabletoexceedonethanwerecorresponding RQtissue, andthisforbothspecies
    Original languageEnglish
    Pages (from-to)240-246
    JournalEcotoxicology and Environmental Safety
    Volume73
    Issue number3
    DOIs
    Publication statusPublished - 2010

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