Uncertainties in ecological, chemical and physiological parameters of a bioaccumulation model: implications for internal concentrations and tissue based risk quotients

F. De Laender; D.J. Van Oevelen; J.J. Middelburg; K.E.R. Soetaert

doi:10.1016/j.ecoenv.2009.11.011

Uncertainties in ecological, chemical and physiological parameters of a bioaccumulation model: implications for internal concentrations and tissue based risk quotients

F. De Laender, D.J. Van Oevelen, J.J. Middelburg, K.E.R. Soetaert

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Abstract

Bioaccumulationmodelspredictinternalcontaminantconcentrations(ci) usingecological,chemical and physiologicalparameters.Hereweanalysetheeffectofuncertaintiesontheseparameterson bioaccumulationmodelpredictions.Simultaneouslyconsideringtheuncertaintiesonallthese parametersinabioaccumulationmodelresultedinuncertaintyrangesof ci that increasedwiththe octanolwaterpartitioncoefficient Kow and reachedmaximaofupto1.25logunitsformesozooplankton and upto1.45logunitsfishatlog Kow=8.Aglobalsensitivityanalysis(SA)wasperformedtorankthe contributionofdifferentparameterstotheobserveduncertainty.TheSAdemonstratedthatthis interspeciesdifferenceresultedpredominantlyfromuncertainproductionratesoffish.The Kow, the water concentrationandorganiccarbon–octanolproportionalityconstantwereimportantdriversof uncertaintyon ci for bothspecies.Atissuebasedriskquotient(RQtissue) combininguncertaintyon ci with realistictissuebasedeffectthresholdsindicatedthatfishwereupto10timesmoreprobableto have RQtissue41 thanmesozooplankton,dependingontheconsideredthresholdvalue.Conventional exposurebasedriskquotientswereupto5timeslessprobabletoexceedonethanwerecorresponding RQtissue, andthisforbothspecies

Original language	English
Pages (from-to)	240-246
Journal	Ecotoxicology and Environmental Safety
Volume	73
Issue number	3
DOIs	https://doi.org/10.1016/j.ecoenv.2009.11.011
Publication status	Published - 2010

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@article{9005bcc06850411a8da86e2efd49bf26,

title = "Uncertainties in ecological, chemical and physiological parameters of a bioaccumulation model: implications for internal concentrations and tissue based risk quotients",

abstract = "Bioaccumulationmodelspredictinternalcontaminantconcentrations(ci) usingecological,chemical and physiologicalparameters.Hereweanalysetheeffectofuncertaintiesontheseparameterson bioaccumulationmodelpredictions.Simultaneouslyconsideringtheuncertaintiesonallthese parametersinabioaccumulationmodelresultedinuncertaintyrangesof ci that increasedwiththe octanolwaterpartitioncoefficient Kow and reachedmaximaofupto1.25logunitsformesozooplankton and upto1.45logunitsfishatlog Kow=8.Aglobalsensitivityanalysis(SA)wasperformedtorankthe contributionofdifferentparameterstotheobserveduncertainty.TheSAdemonstratedthatthis interspeciesdifferenceresultedpredominantlyfromuncertainproductionratesoffish.The Kow, the water concentrationandorganiccarbon–octanolproportionalityconstantwereimportantdriversof uncertaintyon ci for bothspecies.Atissuebasedriskquotient(RQtissue) combininguncertaintyon ci with realistictissuebasedeffectthresholdsindicatedthatfishwereupto10timesmoreprobableto have RQtissue41 thanmesozooplankton,dependingontheconsideredthresholdvalue.Conventional exposurebasedriskquotientswereupto5timeslessprobabletoexceedonethanwerecorresponding RQtissue, andthisforbothspecies",

author = "{De Laender}, F. and {Van Oevelen}, D.J. and J.J. Middelburg and K.E.R. Soetaert",

note = "Reporting year: 2010 Metis note: 4681;CEME; ES; file:///L:\EndnoteDatabases\NIOOPUB\pdfs\PDFS2010\DeLaender_ea_4681.pdf",

year = "2010",

doi = "10.1016/j.ecoenv.2009.11.011",

language = "English",

volume = "73",

pages = "240--246",

journal = "Ecotoxicology and Environmental Safety",

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Uncertainties in ecological, chemical and physiological parameters of a bioaccumulation model: implications for internal concentrations and tissue based risk quotients. / De Laender, F.; Van Oevelen, D.J.; Middelburg, J.J.; Soetaert, K.E.R.

In: Ecotoxicology and Environmental Safety, Vol. 73, No. 3, 2010, p. 240-246.

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

TY - JOUR

T1 - Uncertainties in ecological, chemical and physiological parameters of a bioaccumulation model: implications for internal concentrations and tissue based risk quotients

AU - De Laender, F.

AU - Van Oevelen, D.J.

AU - Middelburg, J.J.

AU - Soetaert, K.E.R.

N1 - Reporting year: 2010 Metis note: 4681;CEME; ES; file:///L:\EndnoteDatabases\NIOOPUB\pdfs\PDFS2010\DeLaender_ea_4681.pdf

PY - 2010

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N2 - Bioaccumulationmodelspredictinternalcontaminantconcentrations(ci) usingecological,chemical and physiologicalparameters.Hereweanalysetheeffectofuncertaintiesontheseparameterson bioaccumulationmodelpredictions.Simultaneouslyconsideringtheuncertaintiesonallthese parametersinabioaccumulationmodelresultedinuncertaintyrangesof ci that increasedwiththe octanolwaterpartitioncoefficient Kow and reachedmaximaofupto1.25logunitsformesozooplankton and upto1.45logunitsfishatlog Kow=8.Aglobalsensitivityanalysis(SA)wasperformedtorankthe contributionofdifferentparameterstotheobserveduncertainty.TheSAdemonstratedthatthis interspeciesdifferenceresultedpredominantlyfromuncertainproductionratesoffish.The Kow, the water concentrationandorganiccarbon–octanolproportionalityconstantwereimportantdriversof uncertaintyon ci for bothspecies.Atissuebasedriskquotient(RQtissue) combininguncertaintyon ci with realistictissuebasedeffectthresholdsindicatedthatfishwereupto10timesmoreprobableto have RQtissue41 thanmesozooplankton,dependingontheconsideredthresholdvalue.Conventional exposurebasedriskquotientswereupto5timeslessprobabletoexceedonethanwerecorresponding RQtissue, andthisforbothspecies

AB - Bioaccumulationmodelspredictinternalcontaminantconcentrations(ci) usingecological,chemical and physiologicalparameters.Hereweanalysetheeffectofuncertaintiesontheseparameterson bioaccumulationmodelpredictions.Simultaneouslyconsideringtheuncertaintiesonallthese parametersinabioaccumulationmodelresultedinuncertaintyrangesof ci that increasedwiththe octanolwaterpartitioncoefficient Kow and reachedmaximaofupto1.25logunitsformesozooplankton and upto1.45logunitsfishatlog Kow=8.Aglobalsensitivityanalysis(SA)wasperformedtorankthe contributionofdifferentparameterstotheobserveduncertainty.TheSAdemonstratedthatthis interspeciesdifferenceresultedpredominantlyfromuncertainproductionratesoffish.The Kow, the water concentrationandorganiccarbon–octanolproportionalityconstantwereimportantdriversof uncertaintyon ci for bothspecies.Atissuebasedriskquotient(RQtissue) combininguncertaintyon ci with realistictissuebasedeffectthresholdsindicatedthatfishwereupto10timesmoreprobableto have RQtissue41 thanmesozooplankton,dependingontheconsideredthresholdvalue.Conventional exposurebasedriskquotientswereupto5timeslessprobabletoexceedonethanwerecorresponding RQtissue, andthisforbothspecies

U2 - 10.1016/j.ecoenv.2009.11.011

DO - 10.1016/j.ecoenv.2009.11.011

M3 - Article

VL - 73

SP - 240

EP - 246

JO - Ecotoxicology and Environmental Safety

JF - Ecotoxicology and Environmental Safety

SN - 0147-6513

IS - 3

ER -

Uncertainties in ecological, chemical and physiological parameters of a bioaccumulation model: implications for internal concentrations and tissue based risk quotients

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