• J.P. van Wijk
  • A.I. Hoepelman
  • E. de Koning
  • G. Dallinga-Thie
  • T.J. Rabelink
  • M.C. Cabezas
OBJECTIVE: To compare the effects of rosiglitazone (8 mg/d, n=19) and metformin (2 g/d, n=18) on postprandial lipemia in patients with HIV-lipodystrophy. METHODS AND RESULTS: Lipodystrophy in HIV is associated with insulin resistance and disturbed postprandial triglyceride and free fatty acid (FFA) metabolism. We conducted an open randomized 6-month study with standardized 10-h oral fat-loading tests at baseline and after treatment. Rosiglitazone (-34%) and metformin (-37%) reduced homeostasis model assessment similarly (P
Original languageEnglish
Pages (from-to)228-233
JournalArtheriosclerosis, Thrombosis and Vascular Biology
Issue number1
StatePublished - 2010

ID: 219459