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DOI

Bioaccumulationmodelspredictinternalcontaminantconcentrations(ci) usingecological,chemical and physiologicalparameters.Hereweanalysetheeffectofuncertaintiesontheseparameterson bioaccumulationmodelpredictions.Simultaneouslyconsideringtheuncertaintiesonallthese parametersinabioaccumulationmodelresultedinuncertaintyrangesof ci that increasedwiththe octanolwaterpartitioncoefficient Kow and reachedmaximaofupto1.25logunitsformesozooplankton and upto1.45logunitsfishatlog Kow=8.Aglobalsensitivityanalysis(SA)wasperformedtorankthe contributionofdifferentparameterstotheobserveduncertainty.TheSAdemonstratedthatthis interspeciesdifferenceresultedpredominantlyfromuncertainproductionratesoffish.The Kow, the water concentrationandorganiccarbon–octanolproportionalityconstantwereimportantdriversof uncertaintyon ci for bothspecies.Atissuebasedriskquotient(RQtissue) combininguncertaintyon ci with realistictissuebasedeffectthresholdsindicatedthatfishwereupto10timesmoreprobableto have RQtissue41 thanmesozooplankton,dependingontheconsideredthresholdvalue.Conventional exposurebasedriskquotientswereupto5timeslessprobabletoexceedonethanwerecorresponding RQtissue, andthisforbothspecies
Original languageEnglish
Pages240-246
JournalEcotoxicology and Environmental Safety
Journal publication date2010
Volume73
Issue3
DOI
StatePublished
Peer-reviewedYes

ID: 388499