The laboratory rat is rapidly gaining momentum as a mammalian genetic model organism. Although traditional forward genetic approaches are well established, recent technological developments have enabled efficient gene targeting and mutant generation. Here we outline the current status, possibilities and application of these techniques in the rat.
Original languageEnglish
Pages (from-to)217
JournalGenome Biology
Volume11
Issue number9
DOI
StatePublished - 2010

ID: 91092