RNAi is essential for pericentromeric heterochromatic formation in S. pombe, and although Dcr1, the initiator protein of this process, has been biochemically well described, its subcellular localization has remained elusive. In this issue of Developmental Cell, Emmerth et al. now show that Dcr1 is dynamically shuttling between nucleus and cytoplasm, adding new insight into the subcellular mechanics of RNAi.
Original languageEnglish
Pages6-7
JournalDevelopmental Cell
Journal publication date2010
Volume18
Issue1
DOI
StatePublished
Peer-reviewedYes

ID: 296670