Hubrecht Institute

Onderzoeksoutput

Onderzoeksoutput per jaar 1985 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2021

• 1793 Artikel
• 145 PhD thesis (Proefschrift)
• 30 Boek/film/artikelrecensie
• 11 Hoofdstuk
• 10 Meer
  • 6 Boek
  • 2 Speciale uitgave (redactielidmaatschap)
  • 1 Bijdrage aan conferentie proceedings
  • 1 Patent

Onderzoeksoutput per jaar

Onderzoeksoutput per jaar

Zoekresultaten

• Speciale uitgave (redactielidmaatschap)

  Celebrating 100 years of Developmental Biology at the Hubrecht Institute

  den Hertog, J. (Gastred.) & van Oudenaarden, A. (Gastred.), 15 aug. 2017, In: Developmental Biology. 428, 2

  Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Speciale uitgave (redactielidmaatschap) › Wetenschappelijk

  • Developmental Biology 100%
  • Stem Cell Research 50%
  • Anniversaries and Special Events 48%

• Molecules: Protein-Tyrosine Phosphatase Inhibitors

  den Hertog, J. (Gastred.), 2018, In: Molecules. Special Issue

  Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Speciale uitgave (redactielidmaatschap) › Wetenschappelijk
• PhD thesis (Proefschrift)

  A bone to pick with zebrafish: chemistry and genetics of osteogenesis

  Mackay, E., 25 nov. 2014, Utrecht: Utrecht University. 128 blz.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Zebrafish 100%
  • Vitamin K 99%
  • Osteogenesis 86%
  • Zinc 82%
  • Bone and Bones 58%

• Aduld Stem Cells in Mice

  Snippert, H. J. G., 2011

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Adult Stem Cell-Derived Kidney Organoids to Model Tissue Physiology and Disease

  Schutgens, F., 21 nov. 2017, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • adult stem cells 100%
  • physiology 52%
  • kidneys 46%
  • tissues 28%
  • stem cells 26%

• Advances in single-cell sequencing technologies and applications in cancer

  Kester, L., 15 mrt. 2018, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  Open Access

  • Technology 100%
  • Organoids 50%
  • Neoplasms 49%
  • Messenger RNA 36%
  • Colonic Neoplasms 34%

• Advance to GO: Regulation of mitotic progression by the spindle checkpoint kinase MPS1

  Pachis, S. T., 24 sep. 2019, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • M Phase Cell Cycle Checkpoints 100%
  • Kinetochores 96%
  • Phosphotransferases 57%
  • Microtubules 35%
  • Chromosomes 29%

• Advancing the flatworm Macrostomum lignano as a versatile model organism for stem cell research.

  Demircan, T., 2013

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  Open Access

  Bestand
  396 Downloads (Pure)

• A high priority shipment : How nuclease delivery by SLX4 mediates DNA interstrand crosslink repair

  Hoogenboom, W. S., 17 dec. 2019, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Fanconi Anemia 100%
  • DNA Replication 56%
  • Mutation 52%
  • DNA 52%
  • Insect Proteins 31%

• A mutagenesis screen in the mouse: Identification of novel gene functions in embryonic development

  Wansleeben, C., 2010

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Applications of next generation sequencing in (epi)genetics

  Mokry, M., 2011

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• A tale of two measurements: protein-DNA interactions and gene expression in single cells. Protein-DNA interactions and gene expression in single cells

  Markodimitraki, C. M., 15 okt. 2020, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Gene Expression 100%
  • DNA 93%
  • Proteins 61%
  • Messenger RNA 47%
  • Adipocytes 17%

• Beyond the Fanconi anemia pathway: new mechanisms of DNA interstrand crosslink repair

  Bolner, A., 09 dec. 2021, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Bmp signaling is at the heart of vertebrate left-right symmetry

  Verhoeven, M. C., 2009, Universiteit Utrecht. 132 blz.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Cancer cell communication through extracellular vesicles

  Steenbeek, S. C., 15 jan. 2019, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Cancer cell plasticity and niche independency drive metastasis in colorectal cancer

  Fumagalli, A., 11 apr. 2019, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Cell Plasticity 100%
  • Colorectal Neoplasms 59%
  • Neoplasm Metastasis 46%
  • Neoplastic Stem Cells 37%
  • Organoids 26%

• Cardiac recovery by stem and progenitor cells

  van Laake, L. W., 2008, 248 blz.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Cdx, Hox and the Genetics of axial extension in the mouse

  van de Ven, C., 2011

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Cdx2 is essential for embryonic axial growth and identity of the adult intestinal stem cells

  Simmini, S., 20 jan. 2015, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  Open Access

  • stem cells 100%
  • stomach 71%
  • tail 41%
  • pylorus 33%
  • epithelium 30%

• Cdx genes and the maintenance of tissue progenitors in the mouse

  Bialecka, M., 2012

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Cdx genes and tissue progenitors in the mouse

  Bialecka, M., 2012

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Cell Fate Determination in Zebrafish Embryonic and Adult Muscle Development

  Tee, J. M., 2010

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Characterisation of human pancreatic organoids: navigating towards islets of Langerhans

  Williams Giuliani, N., 18 jun. 2019, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Organoids 100%
  • Islets of Langerhans 76%
  • Tretinoin 33%
  • Cell- and Tissue-Based Therapy 30%
  • Insulin 29%

• Characterization of islet cells during development and after transplantation

  van Gurp, L., 17 mrt. 2017, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • islets of Langerhans 100%
  • pancreas 32%
  • cells 26%
  • insulin 12%
  • blood glucose 9%

• Characterizing intestinal stem cells - An important part of the puzzle -

  Schepers, A., 2012

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• ChIPping away at intestinal stemness

  Schuijers, J., 2013

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Chromatin conformation capture strategies in molecular diagnostics

  de Vree, P. J. P., 09 jul. 2015, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  Open Access

  • Hereditary Hemorrhagic Telangiectasia 100%
  • Molecular Pathology 81%
  • Chromatin 62%
  • Technology 38%
  • Mutation 19%

• Chromosomal instability in tumorigenesis: The importance of how much, where and when

  Hoevenaar, W., 20 jun. 2019, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • chromosomal instability 100%
  • carcinogenesis 71%
  • neoplasms 19%
  • mice 6%
  • colon 5%

• Chromosome topology underlying factors: studies on a model gene locus and an exemplary DNA looping protein

  Holwerda, S. J., 2013

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Circadian networks in stem cells and their cardiac derivatives

  Dierickx, P., 23 feb. 2017

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Cardiac Myocytes 100%
  • Circadian Clocks 89%
  • Stem Cells 79%
  • Circadian Rhythm 75%
  • Heart Failure 52%

• Cis-regulatory elements in the primate brain: from functional specialization to neurodegeneration

  Vermunt, M. W., 23 feb. 2017

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Primates 100%
  • Brain 52%
  • Synucleins 40%
  • Genetic Enhancer Elements 34%
  • Neurodegenerative Diseases 23%

• Constructing roadmaps towards functional cell types using organoids: Shaping and changing the functions of the intestine

  Beumer, J., 10 sep. 2020, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • intestines 100%
  • cells 38%
  • venoms 33%
  • snake venoms 16%
  • enterocytes 15%

• Contactomics - exploring new dimensions of 3D genome architecture

  Bouwman, B., 23 jun. 2016

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Cutting edge tools to reveal lineages and epigenetic modifications in single cells

  Florescu, M., 29 sep. 2020, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Epigenomics 100%
  • Technology 20%
  • Stem Cells 19%
  • Histone Code 17%
  • Zebrafish 15%

• Decrypting gastrointestinal development and homeostasis one cell at a time

  Wiebrands, K., 06 sep. 2016

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Defining and Mining the Intestinal Stem Cell Signature

  Stange, D. E., 2012

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Dimorphisms in Nematodes

  Ebbing, A. L. P., 30 jan. 2020, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Caenorhabditis elegans 100%
  • Gene Expression 54%
  • Cell Movement 49%
  • Population 35%
  • Sex Characteristics 28%

• Diving into cellular signalling: Functional proteome analysis by mass spectrometry based approaches

  Leijten, N. M., 13 sep. 2021, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• DNA mismatch repair, genome instability and cancer in zebrafish

  Feitsma, H., 2008, Amsterdam: F&N Boekservice. 142 blz.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• DNA repair mechanisms in C. elegans

  Brouwer, K., 2009, Utrecht: Universiteit Utrecht.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Double-strand break repair and G4 DNA stability in Caenorhabditis elegans

  Pontier, D. B., 2010

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Early differentiation dynamics of the trophoblastic lineage and its cross-communication with the embryo

  Frias-Aldeguer, J., 2019, Maastricht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Enhancing Evolution: Charting regulatory changes across primate evolution

  Castelijns, B., 12 nov. 2020, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Epigenetics from covalent modifications to small RNAs.

  Kaaij, L. J., 2013

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Evolution of the Kinetochore Network in Eukaryotes

  Tromer, E., 12 dec. 2017, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  Open Access

  • Kinetochores 100%
  • Eukaryota 78%
  • Microtubules 15%
  • Amino Acid Motifs 13%
  • Chromosome Segregation 13%

• Factors involved in cardiac physiological and pathological remodeling

  Demkes, C. J., 17 apr. 2018, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Cardiac Myocytes 100%
  • Heart 92%
  • MicroRNAs 60%
  • Hypertrophy 32%
  • Genes 28%

• Factors shaping the 3D genome

  Zhu, Y., 07 jul. 2015, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  Open Access

  • Histones 100%
  • Genome 72%
  • Chromatin 70%
  • Trans-Activators 65%
  • Gene Expression 63%

• F-box proteins, cell cycle and cancer

  Kim, J., 13 jan. 2015, utrecht: Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  Open Access

  • SKP Cullin F-Box Protein Ligases 100%
  • F-Box Proteins 91%
  • Ubiquitin-Protein Ligases 51%
  • Cell Cycle 47%
  • Basic Helix-Loop-Helix Transcription Factors 41%

• Finding the way: transcriptional regulation of migratory neuroblast lineages in C. elegans

  Fernandes Póvoa, E. E., 10 jul. 2020, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • RNA-Seq 100%
  • Catenins 72%
  • rho GTPase-activating protein 47%
  • Cell Movement 46%
  • Extravehicular Activity 45%

• Fishing for genes : Using zebrafish to study the functional genetics of cardiac arrhythmias

  Koopman, C. D., 13 jun. 2019, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)