Wouter de Laat

Zoekresultaten

• 2022

  Dynamics and Heterogeneity of mRNA Translation and RNA virus Infections

  Boersma, S., 18 mei 2022, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• How enhancers shape and activate the genome

  Rinzema, N. J., 14 jul. 2022, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)
• 2021

  Gene expression in sight: Single-molecule studies of gene expression control

  Sonneveld, S., 03 nov. 2021, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• The DUX4 cytotoxic cascade, and CRISPR mitigation methods

  Ashoti, A., 17 jun. 2021, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• Visualizing mRNA quality control: Mechanistic insights from translational dynamics

  Hoek, T. A., 09 mrt. 2021, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)
• 2020

  Enhancing Evolution: Charting regulatory changes across primate evolution

  Castelijns, B., 12 nov. 2020, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)
• 2019

  A high priority shipment : How nuclease delivery by SLX4 mediates DNA interstrand crosslink repair

  Hoogenboom, W. S., 17 dec. 2019, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Fanconi Anemia 100%
  • DNA Replication 56%
  • Mutation 52%
  • DNA 52%
  • Insect Proteins 31%

• Gene Control in 3D : The Roles of CTCF and Chromatin Looping in Organizing a Functional Genome

  Vos, E. S. M., 31 okt. 2019, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Chromatin 100%
  • Genome 76%
  • DNA 63%
  • Gene Expression 54%
  • Binding Sites 52%
• 2018

  Resolving allele-specific genetic and architectural variation: Proximity ligations from benchtop to bedside

  Vermeulen, C., 17 apr. 2018, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  Open Access

  • Genetic Variation 100%
  • Ligation 90%
  • Alleles 75%
  • cohesins 42%
  • DNA 41%
• 2017

  Making the cut: How XPF-ERCC1 unhooks DNA interstrand crosslinks

  Klein Douwel, D., 19 jan. 2017, University of Utrecht.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Fanconi Anemia 100%
  • DNA Repair 55%
  • DNA 41%
  • DNA Replication 29%
  • Poisons 22%
• 2016

  Contactomics - exploring new dimensions of 3D genome architecture

  Bouwman, B., 23 jun. 2016

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)
• 2015

  Chromatin conformation capture strategies in molecular diagnostics

  de Vree, P. J. P., 09 jul. 2015, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  Open Access

  • Hereditary Hemorrhagic Telangiectasia 100%
  • Molecular Pathology 81%
  • Chromatin 62%
  • Technology 38%
  • Mutation 19%

• Factors shaping the 3D genome

  Zhu, Y., 07 jul. 2015, Utrecht University.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  Open Access

  • Histones 100%
  • Genome 72%
  • Chromatin 70%
  • Trans-Activators 65%
  • Gene Expression 63%
• 2014

  A bone to pick with zebrafish: chemistry and genetics of osteogenesis

  Mackay, E., 25 nov. 2014, Utrecht: Utrecht University. 128 blz.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Zebrafish 100%
  • Vitamin K 99%
  • Osteogenesis 86%
  • Zinc 82%
  • Bone and Bones 58%

• Endothelial cell specification - Crossroads in vascular development

  Hermkens, D. M. A., 20 nov. 2014, Box Press Publishers. 122 blz.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Endothelial Cells 100%
  • Blood Vessels 79%
  • Arteries 75%
  • Zebrafish 68%
  • Cardiovascular System 66%

• Mechanisms of crosstalk between phosphorylation and ubiquitylation in the regulation of cell proliferation

  D'Annibale, S., 31 okt. 2014, utrecht: University of Utrecht. 102 blz.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Ubiquitination 100%
  • Ubiquitin 92%
  • Proteolysis 86%
  • Ligases 84%
  • Phosphorylation 63%

• Putting crystals in place - the regulation of biomineralization in zebrafish

  Apschner, A., 17 nov. 2014, Utrecht University. 144 blz.

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

  • Biomineralization 100%
  • Zebrafish 69%
  • diphosphoric acid 68%
  • Skeleton 52%
  • Osteoporosis 45%
• 2013

  Chromosome topology underlying factors: studies on a model gene locus and an exemplary DNA looping protein

  Holwerda, S. J., 2013

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• High resolution in vivo imaging of metastasis

  Ritsma, L., 2013

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)

• SCFβTrCP, discovering new sides of the E3 ligase by studying its substrates

  Kruiswijk, F., 2013

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)
• 2011

  Keeping the genome in shape: a role for protein and RNA

  Splinter, E., 2011

  Onderzoeksoutput: PhD Thesis (Proefschrift) › PhD thesis (Proefschrift)