A case of cross-reactivity

H.C. Korswagen

doi:10.1016/j.chembiol.2011.04.003

A case of cross-reactivity

Hubrecht Institute

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

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Studies using chemical inhibitors have suggested that p38 MAP kinase is a key regulator of Wnt/beta-catenin signaling. In this issue, Verkaar et al. (2011) show that cross-reactivity of p38 inhibitors with casein kinase Idelta/varepsilon is responsible for Wnt/beta-catenin pathway inhibition.

Originele taal-2	Engels
Pagina's (van-tot)	409-410
Tijdschrift	Chemistry & Biology
Volume	18
Nummer van het tijdschrift	4
DOI's	https://doi.org/10.1016/j.chembiol.2011.04.003
Status	Gepubliceerd - 2011

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10.1016/j.chembiol.2011.04.003

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title = "A case of cross-reactivity",

abstract = "Studies using chemical inhibitors have suggested that p38 MAP kinase is a key regulator of Wnt/beta-catenin signaling. In this issue, Verkaar et al. (2011) show that cross-reactivity of p38 inhibitors with casein kinase Idelta/varepsilon is responsible for Wnt/beta-catenin pathway inhibition.",

author = "H.C. Korswagen",

note = "Reporting year: 2011",

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doi = "10.1016/j.chembiol.2011.04.003",

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journal = "Chemistry & Biology",

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AB - Studies using chemical inhibitors have suggested that p38 MAP kinase is a key regulator of Wnt/beta-catenin signaling. In this issue, Verkaar et al. (2011) show that cross-reactivity of p38 inhibitors with casein kinase Idelta/varepsilon is responsible for Wnt/beta-catenin pathway inhibition.

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DO - 10.1016/j.chembiol.2011.04.003

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SN - 1074-5521

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SP - 409

EP - 410

JO - Chemistry & Biology

JF - Chemistry & Biology

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A case of cross-reactivity

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