A novel l-arabinose-responsive regulator discovered in the rice-blast fungus Pyricularia oryzae (Magnaporthe oryzae)

Sylvia Klaubauf, Miaomiao Zhou, Marc-Henri Lebrun, Ronald P de Vries, Evy Battaglia

    Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgaveArtikelWetenschappelijkpeer review

    Samenvatting

    In this study we identified the l-arabinose-responsive regulator of Pyricularia oryzae that regulates l-arabinose release and catabolism. Previously we identified the Zn2Cys6 transcription factor (TF), AraR, that has this role in the Trichocomaceae family (Eurotiales), but is absent in other fungi. Candidate Zn2Cys6 TF genes were selected according to their transcript profiles on l-arabinose. Deletion mutants of these genes were screened for their growth phenotype on l-arabinose. One mutant, named Δara1, was further analyzed. Our analysis demonstrated that Ara1 from P. oryzae is the functional analog of AraR from A. niger, while there is no significant sequence similarity between them.

    Originele taal-2Engels
    Pagina's (van-tot)550-8
    Aantal pagina's9
    TijdschriftFEBS Letters
    Volume590
    Nummer van het tijdschrift4
    DOI's
    StatusGepubliceerd - feb 2016

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