Air Ambulance: Antimicrobial Power of Bacterial Volatiles

TY - JOUR

T1 - Air Ambulance: Antimicrobial Power of Bacterial Volatiles

AU - Lammers, A.

AU - Lalk, Michael

AU - Garbeva, Paolina

N1 - 7355, ME; Data archiving: no data (review)

PY - 2022

Y1 - 2022

N2 - We are currently facing an antimicrobial resistance crisis, which means that a lot of bacterial pathogens have developed resistance to common antibiotics. Hence, novel and innovative solutions are urgently needed to combat resistant human pathogens. A new source of antimicrobial compounds could be bacterial volatiles. Volatiles are ubiquitous produced, chemically divers and playing essential roles in intra- and interspecies interactions like communication and antimicrobial defense. In the last years, an increasing number of studies showed bioactivities of bacterial volatiles, including antibacterial, antifungal and anti-oomycete activities, indicating bacterial volatiles as an exciting source for novel antimicrobial compounds. In this review we introduce the chemical diversity of bacterial volatiles, their antimicrobial activities and methods for testing this activity. Concluding, we discuss the possibility of using antimicrobial volatiles to antagonize the antimicrobial resistance crisis.

AB - We are currently facing an antimicrobial resistance crisis, which means that a lot of bacterial pathogens have developed resistance to common antibiotics. Hence, novel and innovative solutions are urgently needed to combat resistant human pathogens. A new source of antimicrobial compounds could be bacterial volatiles. Volatiles are ubiquitous produced, chemically divers and playing essential roles in intra- and interspecies interactions like communication and antimicrobial defense. In the last years, an increasing number of studies showed bioactivities of bacterial volatiles, including antibacterial, antifungal and anti-oomycete activities, indicating bacterial volatiles as an exciting source for novel antimicrobial compounds. In this review we introduce the chemical diversity of bacterial volatiles, their antimicrobial activities and methods for testing this activity. Concluding, we discuss the possibility of using antimicrobial volatiles to antagonize the antimicrobial resistance crisis.

KW - international

KW - Plan_S-Compliant-OA

U2 - 10.3390/antibiotics11010109

DO - 10.3390/antibiotics11010109

M3 - Article

C2 - 35052986

SN - 2079-6382

VL - 11

JO - Antibiotics

JF - Antibiotics

IS - 1

M1 - 109

ER -