Biosynthesis, Evolution and Ecology of Microbial Terpenoids

Mariana Avalos Garcia (Co-auteur), Paolina Garbeva, Lisa Vader, Gilles van Wezel, J.S. Dickschat, Dana Ulanova

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgaveArtikelWetenschappelijkpeer review

Samenvatting

Terpenoids are the largest class of natural products recognised to date. While mostly known to humans as bioactive plant metabolites and part of essential oils, structurally diverse terpenoids are increasingly reported to be produced by microorganisms. For many of the compounds biological functions are yet unknown, but during the past years significant insights have been obtained for the role of terpenoids in microbial chemical ecology. Their functions include stress alleviation, maintenance of cell membrane integrity, photoprotection, attraction or repulsion of organisms, host growth promotion and defense. In this review we discuss the current knowledge of the biosynthesis and evolution of microbial terpenoids, and their ecological and biological roles in aquatic and terrestrial environments. Perspectives on their biotechnological applications, knowledge gaps and questions for future studies are discussed.
Originele taal-2Engels
TijdschriftNatural Product Reports
VolumeIn press
Vroegere onlinedatum2021
DOI's
StatusE-pub ahead of print - 2021

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