TY - UNPB
T1 - Bipolaris oryzae, a novel fungal opportunist causing keratitis
AU - Al-Hatmi, Abdullah
PY - 2015
Y1 - 2015
N2 - We report a case of mycotic keratitis caused by Bipolaris oryzae with predisposing trauma from a foreign body. The fungus was identified by sequencing the internal transcribed spacer (ITS) region, translation elongation factor 1α (TEF1) gene and partial glyceraldehyde-3-phosphate dehydrogenase (GPDH) gene, and the species identity was confirmed on the basis of its characteristic conidial phenotype. The patient was treated with surgical intervention and antifungal agents, including intravenous fluconazole (FLC), oral itraconazole (ITZ), topical 0.15% amphotericin B (AmB) eye drops, and 0.5% FLC eye drops. To our knowledge, this is the first report of mycotic keratitis caused by B. oryzae worldwide.
AB - We report a case of mycotic keratitis caused by Bipolaris oryzae with predisposing trauma from a foreign body. The fungus was identified by sequencing the internal transcribed spacer (ITS) region, translation elongation factor 1α (TEF1) gene and partial glyceraldehyde-3-phosphate dehydrogenase (GPDH) gene, and the species identity was confirmed on the basis of its characteristic conidial phenotype. The patient was treated with surgical intervention and antifungal agents, including intravenous fluconazole (FLC), oral itraconazole (ITZ), topical 0.15% amphotericin B (AmB) eye drops, and 0.5% FLC eye drops. To our knowledge, this is the first report of mycotic keratitis caused by B. oryzae worldwide.
U2 - 10.1016/j.diagmicrobio.2015.11.020
DO - 10.1016/j.diagmicrobio.2015.11.020
M3 - Web article
SP - 61
EP - 65
BT - Bipolaris oryzae, a novel fungal opportunist causing keratitis
ER -