Birth and upgrowth of the Hox topological domains during evolution

Jacqueline Deschamps

doi:10.1038/ng.3514

Birth and upgrowth of the Hox topological domains during evolution

Jacqueline Deschamps

Hubrecht Institute

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

Samenvatting

The recently discovered chromatin compartments called topologically associating domains (TADs) are essential for the three-dimensional organization of regulatory interactions driving gene expression. A new study documents the emergence of a TAD flanking the amphioxus Hox cluster, prefiguring the vertebrate anterior Hox TAD and preceding the appearance of the concurring posterior Hox TAD.

Originele taal-2	Engels
Pagina's (van-tot)	227-8
Aantal pagina's	2
Tijdschrift	Nature Genetics
Volume	48
Nummer van het tijdschrift	3
DOI's	https://doi.org/10.1038/ng.3514
Status	Gepubliceerd - mrt. 2016

Toegang tot document

10.1038/ng.3514

Citeer dit

@article{31c6ea3434014e47abfe2cc1331ce15a,

title = "Birth and upgrowth of the Hox topological domains during evolution",

abstract = "The recently discovered chromatin compartments called topologically associating domains (TADs) are essential for the three-dimensional organization of regulatory interactions driving gene expression. A new study documents the emergence of a TAD flanking the amphioxus Hox cluster, prefiguring the vertebrate anterior Hox TAD and preceding the appearance of the concurring posterior Hox TAD.",

author = "Jacqueline Deschamps",

year = "2016",

month = mar,

doi = "10.1038/ng.3514",

language = "English",

volume = "48",

pages = "227--8",

journal = "Nature Genetics",

issn = "1061-4036",

publisher = "Nature Publishing Group",

number = "3",

}

TY - JOUR

T1 - Birth and upgrowth of the Hox topological domains during evolution

AU - Deschamps, Jacqueline

PY - 2016/3

Y1 - 2016/3

N2 - The recently discovered chromatin compartments called topologically associating domains (TADs) are essential for the three-dimensional organization of regulatory interactions driving gene expression. A new study documents the emergence of a TAD flanking the amphioxus Hox cluster, prefiguring the vertebrate anterior Hox TAD and preceding the appearance of the concurring posterior Hox TAD.

AB - The recently discovered chromatin compartments called topologically associating domains (TADs) are essential for the three-dimensional organization of regulatory interactions driving gene expression. A new study documents the emergence of a TAD flanking the amphioxus Hox cluster, prefiguring the vertebrate anterior Hox TAD and preceding the appearance of the concurring posterior Hox TAD.

U2 - 10.1038/ng.3514

DO - 10.1038/ng.3514

M3 - Article

C2 - 26906681

SN - 1061-4036

VL - 48

SP - 227

EP - 228

JO - Nature Genetics

JF - Nature Genetics

IS - 3

ER -

Birth and upgrowth of the Hox topological domains during evolution

Samenvatting

Toegang tot document

Vingerafdruk

Citeer dit