Cerebellar imaging at ultra-high magnetic fields.

W. Van der Zwaag, D. Timmann, A. Deistung, Nikos Priovoulos

Onderzoeksoutput: Hoofdstuk in boek/boekdeelHoofdstukWetenschappelijkpeer review

Samenvatting

The cerebellum is a finely structured brain area positioned below the occipital lobe. It is involved in tasks ranging from motor tuning to emotional control. The cerebellum can be affected by diseases such as spinocerebellar ataxias or multiple sclerosis, which can both lead to a wide range of symptoms. As the cerebellar cortex is about 1 mm thick or less, cerebellar imaging profits from ultra-high field (UHF) because of the available high spatial resolution. Extra care should be taken to avoid signal loss due to B0 and B1 inhomogeneities. Data processing and analysis can also be a challenge, as only a few tools are dedicated to cerebellum analysis. T1-weighted imaging offers exquisite details of the cerebellar cortex. The iron-rich deep nuclei, especially the dentate nucleus, can be visualized in detail with QSM or other iron-sensitive imaging techniques. Structural imaging at UHF is expected to offer new insights into cerebellar pathologies.
Originele taal-2Engels
TitelAdvances in Magnetic Resonance Technology and Applications. Ultra-High Field Neuro MRI
UitgeverijElsevier/North-Holland Biomedical Press
Hoofdstuk15
Pagina's245-258
StatusGepubliceerd - 2023

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