Clonality and α-a recombination in the Australian Cryptococcus gattii VGII population - an emerging outbreak in Australia

Fabian Carriconde; Félix Gilgado; Ian Arthur; David Ellis; Richard Malik; Nathalie van de Wiele; Vincent Robert; Bart J. Currie; Wieland Meyer

doi:10.1371/journal.pone.0016936

Clonality and α-a recombination in the Australian Cryptococcus gattii VGII population - an emerging outbreak in Australia

Fabian Carriconde, Félix Gilgado, Ian Arthur, David Ellis, Richard Malik, Nathalie van de Wiele, Vincent Robert, Bart J. Currie, Wieland Meyer

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

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Cryptococcus gattii is a basidiomycetous yeast that causes life-threatening disease in humans and animals. Within C. gattii, four molecular types are recognized (VGI to VGIV). The Australian VGII population has been in the spotlight since 2005, when it was suggested as the possible origin for the ongoing outbreak at Vancouver Island (British Columbia, Canada), with same-sex mating being suggested as the driving force behind the emergence of this outbreak, and is nowadays hypothesized as a widespread phenomenon in C. gattii. However, an in-depth characterization of the Australian VGII population is still lacking. The present work aimed to define the genetic variability within the Australian VGII population and determine processes shaping its population structure.

Originele taal-2	Engels
Artikelnummer	e16936
Tijdschrift	PLoS One
Volume	6
Nummer van het tijdschrift	2
DOI's	https://doi.org/10.1371/journal.pone.0016936 https://doi.org/10.1371/journal.pone.0016936
Status	Gepubliceerd - 2011

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title = "Clonality and α-a recombination in the Australian Cryptococcus gattii VGII population - an emerging outbreak in Australia",

abstract = "Cryptococcus gattii is a basidiomycetous yeast that causes life-threatening disease in humans and animals. Within C. gattii, four molecular types are recognized (VGI to VGIV). The Australian VGII population has been in the spotlight since 2005, when it was suggested as the possible origin for the ongoing outbreak at Vancouver Island (British Columbia, Canada), with same-sex mating being suggested as the driving force behind the emergence of this outbreak, and is nowadays hypothesized as a widespread phenomenon in C. gattii. However, an in-depth characterization of the Australian VGII population is still lacking. The present work aimed to define the genetic variability within the Australian VGII population and determine processes shaping its population structure.",

author = "Fabian Carriconde and F{\'e}lix Gilgado and Ian Arthur and David Ellis and Richard Malik and {van de Wiele}, Nathalie and Vincent Robert and Currie, {Bart J.} and Wieland Meyer",

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T1 - Clonality and α-a recombination in the Australian Cryptococcus gattii VGII population - an emerging outbreak in Australia

AU - Carriconde, Fabian

AU - Gilgado, Félix

AU - Arthur, Ian

AU - Ellis, David

AU - Malik, Richard

AU - van de Wiele, Nathalie

AU - Robert, Vincent

AU - Currie, Bart J.

AU - Meyer, Wieland

N1 - Reporting year: 2011

PY - 2011

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N2 - Cryptococcus gattii is a basidiomycetous yeast that causes life-threatening disease in humans and animals. Within C. gattii, four molecular types are recognized (VGI to VGIV). The Australian VGII population has been in the spotlight since 2005, when it was suggested as the possible origin for the ongoing outbreak at Vancouver Island (British Columbia, Canada), with same-sex mating being suggested as the driving force behind the emergence of this outbreak, and is nowadays hypothesized as a widespread phenomenon in C. gattii. However, an in-depth characterization of the Australian VGII population is still lacking. The present work aimed to define the genetic variability within the Australian VGII population and determine processes shaping its population structure.

AB - Cryptococcus gattii is a basidiomycetous yeast that causes life-threatening disease in humans and animals. Within C. gattii, four molecular types are recognized (VGI to VGIV). The Australian VGII population has been in the spotlight since 2005, when it was suggested as the possible origin for the ongoing outbreak at Vancouver Island (British Columbia, Canada), with same-sex mating being suggested as the driving force behind the emergence of this outbreak, and is nowadays hypothesized as a widespread phenomenon in C. gattii. However, an in-depth characterization of the Australian VGII population is still lacking. The present work aimed to define the genetic variability within the Australian VGII population and determine processes shaping its population structure.

U2 - 10.1371/journal.pone.0016936

DO - 10.1371/journal.pone.0016936

M3 - Article

SN - 1932-6203

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JO - PLoS One

JF - PLoS One

IS - 2

M1 - e16936

ER -

Clonality and α-a recombination in the Australian Cryptococcus gattii VGII population - an emerging outbreak in Australia

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