CNVs are associated with genomic architecture in a songbird

Vinicius H. da Silva (Co-auteur), Veronika N. Laine, M Bosse, Kees van Oers, B.W. Dibbits, Marcel E. Visser, Richard P. M. A. Crooijmans, Martien A.M. Groenen

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgaveArtikelWetenschappelijkpeer review

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Samenvatting

Understanding variation in genome structure is essential to understand phenotypic differences within populations and the evolutionary history of species. A promising form of this structural variation is copy number variation (CNV). CNVs can be generated by different recombination mechanisms, such as non-allelic homologous recombination, that rely on specific characteristics of the genome architecture. These structural variants can therefore be more abundant at particular genes ultimately leading to variation in phenotypes under selection. Detailed characterization of CNVs therefore can reveal evolutionary footprints of selection and provide insight in their contribution to phenotypic variation in wild populations.
Originele taal-2Engels
Artikelnummer195
TijdschriftBMC Genomics
Volume19
Nummer van het tijdschrift2
DOI's
StatusGepubliceerd - 2018

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