CNVs are associated with genomic architecture in a songbird

Vinicius H. da Silva; Veronika N. Laine; M Bosse; Kees van Oers; B.W. Dibbits; Marcel E. Visser; Richard P. M. A. Crooijmans; Martien A.M.  Groenen

doi:10.1186/s12864-018-4577-1

CNVs are associated with genomic architecture in a songbird

Vinicius H. da Silva (Co-auteur), Veronika N. Laine, M Bosse, Kees van Oers, B.W. Dibbits, Marcel E. Visser, Richard P. M. A. Crooijmans, Martien A.M. Groenen

NIOO - Animal Ecology (AnE)

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

11 Citaten (Scopus)

191 Downloads (Pure)

Samenvatting

Understanding variation in genome structure is essential to understand phenotypic differences within populations and the evolutionary history of species. A promising form of this structural variation is copy number variation (CNV). CNVs can be generated by different recombination mechanisms, such as non-allelic homologous recombination, that rely on specific characteristics of the genome architecture. These structural variants can therefore be more abundant at particular genes ultimately leading to variation in phenotypes under selection. Detailed characterization of CNVs therefore can reveal evolutionary footprints of selection and provide insight in their contribution to phenotypic variation in wild populations.

Originele taal-2	Engels
Artikelnummer	195
Tijdschrift	BMC Genomics
Volume	19
Nummer van het tijdschrift	2
DOI's	https://doi.org/10.1186/s12864-018-4577-1
Status	Gepubliceerd - 2018

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10.1186/s12864-018-4577-1Licentie: CC BY

6503_daSilvaFinal published version, 1,27 MBLicentie: CC BY

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Data

Affymetrix SNP array data for wild Dutch great tits (Parus major) (Great Tit)
da Silva, V. H. (Maker), Laine, V. (Maker), Bosse, M. (Maker), van Oers, K. (Maker), Dibbits, B. W. (Maker), Visser, M. E. (Maker), Crooijmans, R. P. M. A. (Maker) & Groenen, M. A. M. (Maker), NCBI, 19 feb. 2018
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA415009
Dataset

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T1 - CNVs are associated with genomic architecture in a songbird

AU - da Silva, Vinicius H.

AU - Laine, Veronika N.

AU - Bosse, M

AU - Oers, Kees van

AU - Dibbits, B.W.

AU - Visser, Marcel E.

AU - M. A. Crooijmans, Richard P.

AU - Groenen, Martien A.M.

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PY - 2018

Y1 - 2018

N2 - Understanding variation in genome structure is essential to understand phenotypic differences within populations and the evolutionary history of species. A promising form of this structural variation is copy number variation (CNV). CNVs can be generated by different recombination mechanisms, such as non-allelic homologous recombination, that rely on specific characteristics of the genome architecture. These structural variants can therefore be more abundant at particular genes ultimately leading to variation in phenotypes under selection. Detailed characterization of CNVs therefore can reveal evolutionary footprints of selection and provide insight in their contribution to phenotypic variation in wild populations.

AB - Understanding variation in genome structure is essential to understand phenotypic differences within populations and the evolutionary history of species. A promising form of this structural variation is copy number variation (CNV). CNVs can be generated by different recombination mechanisms, such as non-allelic homologous recombination, that rely on specific characteristics of the genome architecture. These structural variants can therefore be more abundant at particular genes ultimately leading to variation in phenotypes under selection. Detailed characterization of CNVs therefore can reveal evolutionary footprints of selection and provide insight in their contribution to phenotypic variation in wild populations.

KW - national

UR - https://www.ncbi.nlm.nih.gov/bioproject/PRJNA415009

U2 - 10.1186/s12864-018-4577-1

DO - 10.1186/s12864-018-4577-1

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VL - 19

JO - BMC Genomics

JF - BMC Genomics

IS - 2

M1 - 195

ER -

CNVs are associated with genomic architecture in a songbird

Samenvatting

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Andere bestanden en links

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Datasets

Affymetrix SNP array data for wild Dutch great tits (Parus major) (Great Tit)

Citeer dit