Complete Genome Sequence of the Itraconazole Decreased Susceptible Madurella fahalii Type-Strain CBS 129176

Mickey Konings; Bert Gerrits van den Ende; Mirthe W J Raats; Ahmed Hassan Fahal; Wendy W J van de Sande; Ferry Hagen

doi:10.1007/s11046-023-00807-0

Complete Genome Sequence of the Itraconazole Decreased Susceptible Madurella fahalii Type-Strain CBS 129176

Mickey Konings, Bert Gerrits van den Ende, Mirthe W J Raats, Ahmed Hassan Fahal, Wendy W J van de Sande, Ferry Hagen

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

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Madurella fahalii is a causative agent of the implantation mycosis mycetoma with decreased susceptibility to itraconazole, the preferred therapeutic drug to combat mycetoma. Here, we report the M. fahalii type-strain CBS 129176 genome assembly and annotation to identify a glutamic acid insert near the azole-binding pocket in the Cyp51A protein.

Originele taal-2	Engels
Pagina's (van-tot)	6
Tijdschrift	Mycopathologia
Volume	189
Nummer van het tijdschrift	1
DOI's	https://doi.org/10.1007/s11046-023-00807-0
Status	Gepubliceerd - 17 jan. 2024

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10.1007/s11046-023-00807-0

https://link.springer.com/article/10.1007/s11046-023-00807-0

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title = "Complete Genome Sequence of the Itraconazole Decreased Susceptible Madurella fahalii Type-Strain CBS 129176",

abstract = "Madurella fahalii is a causative agent of the implantation mycosis mycetoma with decreased susceptibility to itraconazole, the preferred therapeutic drug to combat mycetoma. Here, we report the M. fahalii type-strain CBS 129176 genome assembly and annotation to identify a glutamic acid insert near the azole-binding pocket in the Cyp51A protein.",

keywords = "Itraconazole/pharmacology, Mycetoma, Azoles, Madurella",

author = "Mickey Konings and {Gerrits van den Ende}, Bert and Raats, {Mirthe W J} and Fahal, {Ahmed Hassan} and {van de Sande}, {Wendy W J} and Ferry Hagen",

note = "{\textcopyright} 2024. The Author(s).",

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doi = "10.1007/s11046-023-00807-0",

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T1 - Complete Genome Sequence of the Itraconazole Decreased Susceptible Madurella fahalii Type-Strain CBS 129176

AU - Konings, Mickey

AU - Gerrits van den Ende, Bert

AU - Raats, Mirthe W J

AU - Fahal, Ahmed Hassan

AU - van de Sande, Wendy W J

AU - Hagen, Ferry

PY - 2024/1/17

Y1 - 2024/1/17

N2 - Madurella fahalii is a causative agent of the implantation mycosis mycetoma with decreased susceptibility to itraconazole, the preferred therapeutic drug to combat mycetoma. Here, we report the M. fahalii type-strain CBS 129176 genome assembly and annotation to identify a glutamic acid insert near the azole-binding pocket in the Cyp51A protein.

AB - Madurella fahalii is a causative agent of the implantation mycosis mycetoma with decreased susceptibility to itraconazole, the preferred therapeutic drug to combat mycetoma. Here, we report the M. fahalii type-strain CBS 129176 genome assembly and annotation to identify a glutamic acid insert near the azole-binding pocket in the Cyp51A protein.

KW - Itraconazole/pharmacology

KW - Mycetoma

KW - Azoles

KW - Madurella

U2 - 10.1007/s11046-023-00807-0

DO - 10.1007/s11046-023-00807-0

M3 - Article

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SN - 0301-486X

VL - 189

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JO - Mycopathologia

JF - Mycopathologia

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Complete Genome Sequence of the Itraconazole Decreased Susceptible Madurella fahalii Type-Strain CBS 129176

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