CONREAL web server: identification and visualization of conserved transcription factor binding sites

TY - JOUR

T1 - CONREAL web server: identification and visualization of conserved transcription factor binding sites

AU - Berezikov, E.

AU - Guryev, V.

AU - Cuppen, E.

N1 - Reporting year: 2005 Metis note: 15980509

PY - 2005

Y1 - 2005

N2 - The use of orthologous sequences and phylogenetic footprinting approaches have become popular for the recognition of conserved and potentially functional sequences. Several algorithms have been developed for the identification of conserved transcription factor binding sites (TFBSs), which are characterized by their relatively short and degenerative recognition sequences. The CONREAL (conserved regulatory elements anchored alignment) web server provides a versatile interface to CONREAL-, LAGAN-, BLASTZ- and AVID-based predictions of conserved TFBSs in orthologous promoters. Comparative analysis using different algorithms can be started by keyword without any prior sequence retrieval. The interface is available at http://conreal.niob.knaw.nl.

AB - The use of orthologous sequences and phylogenetic footprinting approaches have become popular for the recognition of conserved and potentially functional sequences. Several algorithms have been developed for the identification of conserved transcription factor binding sites (TFBSs), which are characterized by their relatively short and degenerative recognition sequences. The CONREAL (conserved regulatory elements anchored alignment) web server provides a versatile interface to CONREAL-, LAGAN-, BLASTZ- and AVID-based predictions of conserved TFBSs in orthologous promoters. Comparative analysis using different algorithms can be started by keyword without any prior sequence retrieval. The interface is available at http://conreal.niob.knaw.nl.

U2 - 10.1093/nar/gki378

DO - 10.1093/nar/gki378

M3 - Article

SN - 0305-1048

VL - 33

SP - 447

EP - 450

JO - Nucleic Acids Research

JF - Nucleic Acids Research

IS - Web Server issue

ER -