Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress

Biochemistry, Genetics and Molecular Biology

• Adenosine Monophosphate 8%
• Autophosphorylation 8%
• Binding Domain 8%
• Cell Cycle 8%
• DNA Damage 8%
• DNA Damage Checkpoint 8%
• Elongation Factor 2 100%
• Elongation Factor 2 Kinase 8%
• Eukaryotic Elongation Factors 100%
• F-Box Protein 8%
• Kinase 100%
• Messenger RNA 8%
• P-Site 8%
• phosphorylation 25%
• Phosphotransferase 100%
• Proteasome 8%
• Protein Biosynthesis 100%
• Protein Kinase 8%
• Serine 8%
• Skp1 8%
• Threonine 16%
• Transfer RNA 8%
• Translation Elongation 25%
• Ubiquitin 8%
• Ubiquitin Ligase 8%
• WD40 Repeat 8%

Keyphrases

• Adenosine Monophosphate-activated Protein Kinase 9%
• Autophosphorylation 9%
• Cell Cycle Re-entry 9%
• Chain Elongation 9%
• CUL1 9%
• DNA Damage Checkpoint 9%
• DNA Damage Signaling 9%
• EEF2 100%
• F-box Protein 9%
• Genotoxic Stress 100%
• Ligand-binding Domain 9%
• P-site 9%
• Phosphorylation 27%
• Protein Synthesis 100%
• Rapid Resumption 9%
• SKP1 9%
• Threonine 18%
• Transfer RNA (tRNA) 9%
• Translation Elongation 27%
• Ubiquitin Ligase 9%
• Ubiquitin-proteasome System 9%
• β-transducin Repeat-containing Protein 9%
• β-TrCP 9%