CREB expression in the brains of two closely related parasitic wasp species that differ in long-term memory formation

M. Van den Berg, P. Verbaarschot, S. Hontelez, L.E.M. Vet, M. Dicke, H.M. Smid

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgaveArtikelWetenschappelijkpeer review

Samenvatting

The cAMP/PKA signalling pathway and transcription factor cAMP response element-binding protein (CREB) play key roles in long-term memory (LTM) formation. We used two closely related parasitic wasp species, Cotesia glomerata and Cotesia rubecula, which were previously shown to be different in LTM formation, and sequenced at least nine different CREB transcripts in both wasp species. The splicing patterns, functional domains and amino acid sequences were similar to those found in the CREB genes of other organisms. The predicted amino acid sequences of the CREB isoforms were identical in both wasp species. Using real-time quantitative PCR we found that two low abundant CREB transcripts are differentially expressed in the two wasps, whereas the expression levels of high abundant transcripts are similar.
Originele taal-2Engels
Pagina's (van-tot)367-379
TijdschriftInsect Molecular Biology
Volume19
Nummer van het tijdschrift3
DOI's
StatusGepubliceerd - 2010

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