Defining outcomes for beta cell replacement therapy: a work in progress

Lorenzo Piemonti; Eelco J P de Koning; Thierry Berney; Jon S Odorico; James F Markmann; Peter G Stock; Michael R Rickels

doi:10.1007/s00125-018-4588-0

Defining outcomes for beta cell replacement therapy: a work in progress

Lorenzo Piemonti, Eelco J P de Koning, Thierry Berney, Jon S Odorico, James F Markmann, Peter G Stock, Michael R Rickels

Hubrecht Institute

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

13 Citaten (Scopus)

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Defined outcomes for beta cell replacement therapy in the treatment of diabetes are critically needed. Progress towards the clinical acceptance of pancreas and islet transplantation has been hampered by the lack of clear definitions of functional and efficacy outcomes, as well as a lack of consistently applied glycaemic control metrics, together with poor alignment with the field of artificial insulin delivery/artificial pancreas development. To address this problem, the International Pancreas & Islet Transplant Association (IPITA) collaborated with the European Pancreas and Islet Transplant Association (EPITA) to develop a consensus for a joint statement on the definition of function and failure of beta cell replacement therapies, which is summarised in this commentary.

Originele taal-2	Engels
Pagina's (van-tot)	1273-1276
Aantal pagina's	4
Tijdschrift	Diabetologia
Volume	61
Nummer van het tijdschrift	6
DOI's	https://doi.org/10.1007/s00125-018-4588-0
Status	Gepubliceerd - jun. 2018

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title = "Defining outcomes for beta cell replacement therapy: a work in progress",

abstract = "Defined outcomes for beta cell replacement therapy in the treatment of diabetes are critically needed. Progress towards the clinical acceptance of pancreas and islet transplantation has been hampered by the lack of clear definitions of functional and efficacy outcomes, as well as a lack of consistently applied glycaemic control metrics, together with poor alignment with the field of artificial insulin delivery/artificial pancreas development. To address this problem, the International Pancreas & Islet Transplant Association (IPITA) collaborated with the European Pancreas and Islet Transplant Association (EPITA) to develop a consensus for a joint statement on the definition of function and failure of beta cell replacement therapies, which is summarised in this commentary.",

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author = "Lorenzo Piemonti and {de Koning}, {Eelco J P} and Thierry Berney and Odorico, {Jon S} and Markmann, {James F} and Stock, {Peter G} and Rickels, {Michael R}",

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AU - de Koning, Eelco J P

AU - Berney, Thierry

AU - Odorico, Jon S

AU - Markmann, James F

AU - Stock, Peter G

AU - Rickels, Michael R

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AB - Defined outcomes for beta cell replacement therapy in the treatment of diabetes are critically needed. Progress towards the clinical acceptance of pancreas and islet transplantation has been hampered by the lack of clear definitions of functional and efficacy outcomes, as well as a lack of consistently applied glycaemic control metrics, together with poor alignment with the field of artificial insulin delivery/artificial pancreas development. To address this problem, the International Pancreas & Islet Transplant Association (IPITA) collaborated with the European Pancreas and Islet Transplant Association (EPITA) to develop a consensus for a joint statement on the definition of function and failure of beta cell replacement therapies, which is summarised in this commentary.

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KW - Glycated Hemoglobin A/analysis

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KW - Pancreas Transplantation/methods

KW - Patient Satisfaction

KW - Societies, Medical

KW - Treatment Outcome

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Defining outcomes for beta cell replacement therapy: a work in progress

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