Samenvatting
MicroRNAs (miRNAs) play key regulatory roles in diverse biological processes and are frequently dysregulated in human diseases. Thus, miRNAs have emerged as a class of promising targets for therapeutic intervention. Here, we describe the current strategies for therapeutic modulation of miRNAs and provide an update on the development of miRNA-based therapeutics for the treatment of cancer, cardiovascular disease and hepatitis C virus (HCV) infection.
Originele taal-2 | Engels |
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Pagina's (van-tot) | 851-64 |
Aantal pagina's | 14 |
Tijdschrift | EMBO Molecular Medicine |
Volume | 6 |
Nummer van het tijdschrift | 7 |
DOI's | |
Status | Gepubliceerd - jul. 2014 |