Differential effects of rosiglitazone and metformin on postprandial lipemia in patients with HIV-lipodystrophy

J.P. van Wijk; A.I. Hoepelman; E. de Koning; G. Dallinga-Thie; T.J. Rabelink; M.C. Cabezas

doi:10.1161/ATVBAHA.110.216192

Differential effects of rosiglitazone and metformin on postprandial lipemia in patients with HIV-lipodystrophy

J.P. van Wijk, A.I. Hoepelman, E. de Koning, G. Dallinga-Thie, T.J. Rabelink, M.C. Cabezas

Hubrecht Institute

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

15 Citaten (Scopus)

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OBJECTIVE: To compare the effects of rosiglitazone (8 mg/d, n=19) and metformin (2 g/d, n=18) on postprandial lipemia in patients with HIV-lipodystrophy. METHODS AND RESULTS: Lipodystrophy in HIV is associated with insulin resistance and disturbed postprandial triglyceride and free fatty acid (FFA) metabolism. We conducted an open randomized 6-month study with standardized 10-h oral fat-loading tests at baseline and after treatment. Rosiglitazone (-34%) and metformin (-37%) reduced homeostasis model assessment similarly (P

Originele taal-2	Engels
Pagina's (van-tot)	228-233
Tijdschrift	Artheriosclerosis, Thrombosis and Vascular Biology
Volume	31
Nummer van het tijdschrift	1
DOI's	https://doi.org/10.1161/ATVBAHA.110.216192
Status	Gepubliceerd - 2010

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10.1161/ATVBAHA.110.216192

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title = "Differential effects of rosiglitazone and metformin on postprandial lipemia in patients with HIV-lipodystrophy",

abstract = "OBJECTIVE: To compare the effects of rosiglitazone (8 mg/d, n=19) and metformin (2 g/d, n=18) on postprandial lipemia in patients with HIV-lipodystrophy. METHODS AND RESULTS: Lipodystrophy in HIV is associated with insulin resistance and disturbed postprandial triglyceride and free fatty acid (FFA) metabolism. We conducted an open randomized 6-month study with standardized 10-h oral fat-loading tests at baseline and after treatment. Rosiglitazone (-34%) and metformin (-37%) reduced homeostasis model assessment similarly (P",

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Differential effects of rosiglitazone and metformin on postprandial lipemia in patients with HIV-lipodystrophy. / van Wijk, J.P.; Hoepelman, A.I.; de Koning, E. et al.
In: Artheriosclerosis, Thrombosis and Vascular Biology, Vol. 31, Nr. 1, 2010, blz. 228-233.

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

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T1 - Differential effects of rosiglitazone and metformin on postprandial lipemia in patients with HIV-lipodystrophy

AU - van Wijk, J.P.

AU - Hoepelman, A.I.

AU - de Koning, E.

AU - Dallinga-Thie, G.

AU - Rabelink, T.J.

AU - Cabezas, M.C.

N1 - Reporting year: 2010 Metis note: ATVBAHA.110.216192 [pii]

PY - 2010

Y1 - 2010

N2 - OBJECTIVE: To compare the effects of rosiglitazone (8 mg/d, n=19) and metformin (2 g/d, n=18) on postprandial lipemia in patients with HIV-lipodystrophy. METHODS AND RESULTS: Lipodystrophy in HIV is associated with insulin resistance and disturbed postprandial triglyceride and free fatty acid (FFA) metabolism. We conducted an open randomized 6-month study with standardized 10-h oral fat-loading tests at baseline and after treatment. Rosiglitazone (-34%) and metformin (-37%) reduced homeostasis model assessment similarly (P

AB - OBJECTIVE: To compare the effects of rosiglitazone (8 mg/d, n=19) and metformin (2 g/d, n=18) on postprandial lipemia in patients with HIV-lipodystrophy. METHODS AND RESULTS: Lipodystrophy in HIV is associated with insulin resistance and disturbed postprandial triglyceride and free fatty acid (FFA) metabolism. We conducted an open randomized 6-month study with standardized 10-h oral fat-loading tests at baseline and after treatment. Rosiglitazone (-34%) and metformin (-37%) reduced homeostasis model assessment similarly (P

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DO - 10.1161/ATVBAHA.110.216192

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JO - Artheriosclerosis, Thrombosis and Vascular Biology

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Differential effects of rosiglitazone and metformin on postprandial lipemia in patients with HIV-lipodystrophy

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