Diversity of Bipolaris species in clinical samples in the United States and their antifungal susceptibility profiles

K.C. da Cunha, D.A. Sutton, A.W. Fothergill, J. Cano, J. Gene, H. Madrid, S. de Hoog, P.W. Crous, J. Guarro

    Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgaveArtikelWetenschappelijkpeer review

    58 Citaten (Scopus)

    Samenvatting

    A set of 104 isolates from human clinical samples from the United States, morphologically compatible with Bipolaris, were morphologically and molecularly identified through the sequence analysis of the internal transcribed space (ITS) region of the nuclear ribosomal DNA (rDNA). The predominant species was Bipolaris spicifera (67.3%), followed by B. hawaiiensis (18.2%), B. cynodontis (8.6%), B. micropus (2.9%), B. australiensis (2%), and B. setariae (1%). Bipolaris cynodontis, B. micropus, and B. setariae represent new records from clinical samples. The most common anatomical sites where isolates were recovered were the nasal region (30.7%), skin (19.2%), lungs (14.4%), and eyes (12.5%). The antifungal susceptibilities of 5 species of Bipolaris to 9 drugs are provided. With the exception of fluconazole and flucytosine, the antifungals tested showed good activity.
    Originele taal-2Engels
    Pagina's (van-tot)4061-4066
    TijdschriftJournal of Clinical Microbiology
    Volume50
    Nummer van het tijdschrift12
    DOI's
    StatusGepubliceerd - 2012

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