Fatal Cryptococcus gattii genotype AFLP5 infection in an immunocompetent Cuban patient

María T Illnait-Zaragozí; Lilia M Ortega-Gonzalez; Ferry Hagen; Gerardo F Martínez-Machin; Jacques F Meis

doi:10.1016/j.mmcr.2013.02.001

Fatal Cryptococcus gattii genotype AFLP5 infection in an immunocompetent Cuban patient

María T Illnait-Zaragozí, Lilia M Ortega-Gonzalez, Ferry Hagen, Gerardo F Martínez-Machin, Jacques F Meis

Westerdijk Fungal Biodiversity Institute

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

17 Citaten (Scopus)

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We describe the first clinical case of cryptococcosis due C. gattii in a Cuban immunocompetent patient who had a traveling history two years before to Central America. Molecular characterization of the isolate showed it to be genotype AFLP5 of which MLST sequences clustered with clinical and environmental strains from Colombia. The patient died one year after the diagnosis despite a prolonged treatment with (liposomal) amphotericin B, fluconazole, voriconazole and gamma interferon.

Originele taal-2	Engels
Pagina's (van-tot)	48-51
Aantal pagina's	4
Tijdschrift	Medical Mycology Case Reports
Volume	2
DOI's	https://doi.org/10.1016/j.mmcr.2013.02.001
Status	Gepubliceerd - 09 feb. 2013

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abstract = "We describe the first clinical case of cryptococcosis due C. gattii in a Cuban immunocompetent patient who had a traveling history two years before to Central America. Molecular characterization of the isolate showed it to be genotype AFLP5 of which MLST sequences clustered with clinical and environmental strains from Colombia. The patient died one year after the diagnosis despite a prolonged treatment with (liposomal) amphotericin B, fluconazole, voriconazole and gamma interferon. ",

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AU - Illnait-Zaragozí, María T

AU - Ortega-Gonzalez, Lilia M

AU - Hagen, Ferry

AU - Martínez-Machin, Gerardo F

AU - Meis, Jacques F

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N2 - We describe the first clinical case of cryptococcosis due C. gattii in a Cuban immunocompetent patient who had a traveling history two years before to Central America. Molecular characterization of the isolate showed it to be genotype AFLP5 of which MLST sequences clustered with clinical and environmental strains from Colombia. The patient died one year after the diagnosis despite a prolonged treatment with (liposomal) amphotericin B, fluconazole, voriconazole and gamma interferon.

AB - We describe the first clinical case of cryptococcosis due C. gattii in a Cuban immunocompetent patient who had a traveling history two years before to Central America. Molecular characterization of the isolate showed it to be genotype AFLP5 of which MLST sequences clustered with clinical and environmental strains from Colombia. The patient died one year after the diagnosis despite a prolonged treatment with (liposomal) amphotericin B, fluconazole, voriconazole and gamma interferon.

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Fatal Cryptococcus gattii genotype AFLP5 infection in an immunocompetent Cuban patient

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