For genomes to stay in shape, insulators must be up to PAR

P.J. Wijchers; W. de Laat

doi:10.1016/j.cell.2013.09.012

For genomes to stay in shape, insulators must be up to PAR

P.J. Wijchers
, W. de Laat

Hubrecht Institute

Onderzoeksoutput: Bijdrage aan wetenschappelijk tijdschrift/periodieke uitgave › Artikel › Wetenschappelijk › peer review

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Insulators drive nuclear organization by blocking or facilitating interactions between DNA regulatory elements. Ong et al. show that poly(ADP-ribosyl)ation of insulator binding proteins modulates their ability to physically interact with distant regulatory elements, implicating posttranslational modifications of nonhistone proteins in genome architecture.

Originele taal-2	Engels
Pagina's (van-tot)	15-16
Tijdschrift	Cell
Volume	155
Nummer van het tijdschrift	1
DOI's	https://doi.org/10.1016/j.cell.2013.09.012
Status	Gepubliceerd - 2013

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10.1016/j.cell.2013.09.012

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title = "For genomes to stay in shape, insulators must be up to PAR",

abstract = "Insulators drive nuclear organization by blocking or facilitating interactions between DNA regulatory elements. Ong et al. show that poly(ADP-ribosyl)ation of insulator binding proteins modulates their ability to physically interact with distant regulatory elements, implicating posttranslational modifications of nonhistone proteins in genome architecture.",

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For genomes to stay in shape, insulators must be up to PAR

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